4600 W Nobel St, Sioux Falls, SD 57107

https://www.youtube.com/watch?v=vLG5zsCQHSw

Ryan Oines

PRO

$21 - $27/SF/YR

420 days on market

Updated 40 days ago

USD Discovery District (Research Park)

Building Details

Property Type

Industrial, Land (+1)

Sub Type

Traditional Office, Manufacturing (+1)

Tenancy

Multiple

Lease Type

NNN

Class

Total Building SqFt

50,000

Min Divisible SqFt

970

Max Contiguous SqFt

8,000

Vacant SqFt

23,018

Ceiling Height

14 feet

Total Parking Spaces

200

Year Built

2025

Spaces

Discover a versatile core and shell space ready to be tailored to your needs! With 950–4,838 sq. ft. available, this space offers the flexibility to design a layout that fits your vision. Our experienced developers will customize the space to your exact specifications. Conveniently located near the interstate, with Amazon and Owens & Minor across the street, this location optimizes distribution for medical and non-medical products. Lease today!

Discover a versatile core and shell space ready to be tailored to your needs! With 2000–8,000 sq. ft. available, this space offers the flexibility to design a layout that fits your vision. Our experienced developers will customize the space to your exact specifications. Conveniently located near the interstate, with Amazon and Owens & Minor across the street, this location optimizes distribution for medical and non-medical products. Lease today!

Discover a versatile core and shell space ready to be tailored to your needs! With 2000–6,200 sq. ft. available, this space offers the flexibility to design a layout that fits your vision. Our experienced developers will customize the space to your exact specifications. Conveniently located near the interstate, with Amazon and Owens & Minor across the street, this location optimizes distribution for medical and non-medical products. Lease today!

Discover a versatile core and shell space ready to be tailored to your needs! With 970 sq. ft. available, this space offers the flexibility to design a layout that fits your vision. Our experienced developers will customize the space to your exact specifications. Conveniently located near the interstate, with Amazon and Owens & Minor across the street, this location optimizes distribution for medical and non-medical products. Lease today!

Discover a versatile core and shell space ready to be tailored to your needs! With 2700 sq. ft. available, this space offers the flexibility to design a layout that fits your vision. Our experienced developers will customize the space to your exact specifications. Conveniently located near the interstate, with Amazon and Owens & Minor across the street, this location optimizes distribution for medical and non-medical products. Lease today!

Office/Lab Built to Suite ( ranging from 970 sq. ft. to 8,000 sq. ft)

Building description

Located in Sioux Falls, South Dakota, the USD Discovery District is a premier biotech and life sciences hub designed to foster innovation, collaboration, and economic growth. With the opportunity to custom design and build state-of-the-art lab and office spaces, access to university research and STEM talent, and a strategic location near I-90, I-29, Amazon, and Owens & Minor, this 80+ acre research park is the perfect place for biotech startups, life science companies, and tech-driven enterprises to scale their impact.

Our 50,000 sq. ft. multi-tenant facility, completed in January 2025, offers customizable leasing opportunities with build-to-suit office and lab spaces. Tenants benefit from proximity to Sanford Health, Avera, cutting-edge research programs from the University of South Dakota, and a thriving business ecosystem.

With no state income tax, a low regulatory burden, and a high quality of life, South Dakota provides a business-friendly environment for companies looking to grow. Whether you're an early-stage startup or an established firm, the USD Discovery District is the perfect place for biotech and life science companies, and tech-driven enterprises to scale their impact.

Join a community of innovators. Lease your space today!

Location: Sioux Falls, SD | Contact: [email protected] | usddiscovery.com

Building highlights

Customizable Spaces – Our 50,000 sq. ft. multi-tenant facility is designed for biotech, life sciences, and tech-driven enterprises. We offer build-to-suit lab and office spaces, ensuring each tenant’s unique needs are met.

Strategic Location – Located in Sioux Falls, SD, near I-90 and I-29, the Discovery District provides easy access to major distribution centers like Amazon and Owens & Minor, making logistics seamless for medical and non-medical product distribution.

Advanced Infrastructure – Our facility includes industrial-grade drainage every 40 feet, essential for lab environments, cleanrooms, and specialized biotech operations.

Access to Talent & Research – Tenants benefit from proximity to USD’s Biomedical Engineering Department, Sanford School of Medicine, and STEM workforce, including graduate and PhD-level researchers.

Business-Friendly Environment – South Dakota offers no state income tax, a low regulatory burden, and strong industry support, making it an ideal location for business growth.

Connected Innovation Hub – With partnerships in NSF I-Corps, Sanford Health, and major research institutions, the Discovery District is a catalyst for breakthroughs in biotech, healthcare, and life sciences.

Lease today and customize your ideal workspace!

Contact: [email protected] | usddiscovery.com

Listing Contacts

Ryan Oines

PRO

Map

Property History

Upgrade to Intelligence

Similar Properties

View All

*All information is deemed reliable but not guaranteed. Lessee to verify all information.
Is there information that looks off?