www.crexi.com - The Commercial Real Estate Exchange
For Lease
Special Purpose 

South Carolina Special Purpose Spaces for Lease

393 spaces
Recommended 
Pictures of Office, Industrial, Special Purpose property located at 1007 Bankton Cir, Hanahan, SC 29410 for lease - image #1
$15/SF/YR
1007 Bankton Circle
Flex Office Warehouse • 2 spaces available • 1,822 SqFt - 2,961 SqFt

1007 Bankton Cir Hanahan, SC 29410

Pictures of Special Purpose property located at 1300 Elm Street W # C, Hampton, SC 29924 for lease - image #1
$14/SF/YR
1300 Elm Street W # C
Special Purpose • Single tenant • 1,941 SqFt - 4,261 SqFt

1300 Elm Street W # C Hampton, SC 29924

Pictures of Special Purpose property located at 1028 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464 for lease - image #1
$35 - $40/SF/YR
1028 Johnnie Dodds Boulevard
Special Purpose • Single tenant • 2,884 SqFt - 10,085 SqFt

1028 Johnnie Dodds Boulevard Mount Pleasant, SC 29464

Pictures of Retail, Land, Special Purpose property located at 103 KILLIAN RD, COLUMBIA, SC 29203-9525 for lease - image #1
$125,000/Acre/YR
Killian Rd & Wilson Blvd Signalized Hard Corner-GROUND LEASE
Ground Lease • $125k per Acre • 7.18 acre •

103 KILLIAN RD COLUMBIA, SC 29203-9525

Pictures of Restaurant, Special Purpose property located at 1301 N Cashua Dr, Florence, SC 29501 for lease - image #1
$11.96/SF/YR
1301 N Cashua Dr
±4,416 SF • Former Restaurant/Convenience Store

1301 N Cashua Dr Florence, SC 29501

Pictures of Special Purpose property located at 5550 Rivers Avenue, North Charleston, SC 29406 for lease - image #1
video
$17/SF/YR
5550 Rivers Avenue
Special Purpose • Single tenant • 22,000 SqFt

5550 Rivers Avenue North Charleston, SC 29406

INTELLIGENCE
Instantly evaluate properties and markets with confidence.
Analyze data, market trends, sales comps, demographics, and more.
Learn More
Pictures of Retail, Office, Special Purpose property located at 114 E Gay St, Lancaster, SC 29720 for lease - image #1
video
Undisclosed Rate
Retail /Office - Downtown Lancaster, SC
Exciting Opportunity in Downtown Lancaster

114 E Gay St Lancaster, SC 29720

Pictures of Retail, Special Purpose property located at 27 N Williamsburg County Hwy, Kingstree, Kingstree, US 29556 for lease - image #1
Undisclosed Rate
Former Auto Retailer Space
Retail • 7,195 SF Space for Lease

27 N Williamsburg County Hwy, Kingstree Kingstree, US

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Retail, Office, Special Purpose property located at 1420 Ribaut Road, Port Royal, SC 29935 for lease - image #1
$25.79/SF/YR
1420 Ribaut Road #D
1,675+-sf space for Lease

1420 Ribaut Road Port Royal, SC 29935

Pictures of Retail, Office, Special Purpose property located at 115 Webb Street, Simpsonville, SC 29681 for lease - image #1
$28.80/SF/YR
115 Webb Street
Retail • 1 space available • 1,000 SqFt

115 Webb Street Simpsonville, SC 29681

Pictures of Retail, Office, Special Purpose property located at 3570 Abbeville Highway, Anderson, SC 29624 for lease - image #1
$12.50/SF/YR
3570 Abbeville Highway
2,025 SF Office Available

3570 Abbeville Highway Anderson, SC 29624

Pictures of Special Purpose property located at 698 Mount Bethel Road, Sunset, SC 29685 for lease - image #1
$0.81/SF/MO
698 Mount Bethel Road
Versatile, Spacious 3-Bay Metal Garage - Commercial Space

698 Mount Bethel Road Sunset, SC 29685

Pictures of Office, Special Purpose property located at 711 Bladen Street, Beaufort, SC 29902 for lease - image #1
$90/SF/YR
711 Bladen Street, suite 310

711 Bladen Street Beaufort, SC 29902

Pictures of Office, Special Purpose property located at 1335 44th Avenue North, Myrtle Beach, SC 29577 for lease - image #1
$28/SF/YR
1335 44th Avenue North Suite 201

1335 44th Avenue North Myrtle Beach, SC 29577

Pictures of Special Purpose, Office, Retail property located at 11935 Plaza Dr, Murrells Inlet, SC 29576 for lease - image #1
virtual tour
$35/SF/MO
Plaza Drive
Special Purpose • Single tenant • 3,500 SqFt

11935 Plaza Dr Murrells Inlet, SC 29576

Pictures of Special Purpose property located at Brighton Park Boulevard #Building E, Summerville, SC 29486 for lease - image #1
$37/SF/YR
Brighton Park Boulevard #Building E
Special Purpose • Single tenant • 5,300 SqFt

Brighton Park Boulevard #Building E Summerville, SC 29486

Pictures of Special Purpose property located at Blueway Avenue # B #A & B, Summerville, SC 29483 for lease - image #1
$35/SF/YR
Blueway Avenue # B #A & B
Special Purpose • Single tenant • 1,200 SqFt - 5,470 SqFt

Blueway Avenue # B #A & B Summerville, SC 29483

Pictures of Special Purpose property located at 1345 Nexton Parkway, Summerville, SC 29483 for lease - image #1
$55/SF/YR
1345 Nexton Parkway
Special Purpose • 2 spaces available • 15,000 SqFt - 22,000 SqFt

1345 Nexton Parkway Summerville, SC 29483

Pictures of Special Purpose property located at 1783 Harmon Street, North Charleston, SC 29405 for lease - image #1
$13.50/SF/YR
1783 Harmon Street
Special Purpose • Single tenant • 3,600 SqFt

1783 Harmon Street North Charleston, SC 29405

Pictures of Restaurant, Special Purpose property located at 2304 N Kings Hwy, Myrtle Beach, SC 29577 for lease - image #1
$21/SF/YR
Fast Food Follies
Restaurant • Single tenant

2304 N Kings Hwy Myrtle Beach, SC 29577

Pictures of Special Purpose property located at 1750 Remount Road # D, Charleston, SC 29406 for lease - image #1
$25/SF/YR
1750 Remount Road # D
Special Purpose • Single tenant • 2,400 SqFt - 4,800 SqFt

1750 Remount Road # D Charleston, SC 29406

Pictures of Office, Special Purpose property located at New Riverside Vlg Wy, Bluffton, SC 29910 for lease - image #1
$43/SF/YR
Class A Office Space In New Riverside Village
Office • 1 space available - 1,899 SF

New Riverside Vlg Wy Bluffton, SC 29910

Pictures of Special Purpose property located at 0 N Highway 17, Mount Pleasant, SC 29464 for lease - image #1
$100,000 - $180,000/SF/YR
0 N Highway 17
Special Purpose • Single tenant • 40,000 SqFt

0 N Highway 17 Mount Pleasant, SC 29464

Pictures of Office, Special Purpose property located at 1924 MCCONNELL SPGS RD, ANDERSON, SC 29621 for lease - image #1
$12.43/SF/YR
MCCONNELL SPRINGS RD ANDERSON SC 29621
Located Just off Hwy 81 N in Anderson, SC

1924 MCCONNELL SPGS RD ANDERSON, SC 29621

Pictures of Retail, Industrial, Special Purpose property located at 190 Pontiac Business Center Dr, Elgin, SC 29045 for lease - image #1
$1.31/SF/YR
190 Pontiac Business Center Dr
Retail • Single tenant • 40,803 SqFt

190 Pontiac Business Center Dr Elgin, SC 29045

Pictures of Retail, Office, Special Purpose property located at 8 Celadon Dr unit B, Beaufort, SC 29907 for lease - image #1
$1.50/SF/MO
8 Celadon Dr Unit B
Retail • Single tenant • 1,100 SqFt

8 Celadon Dr unit B Beaufort, SC 29907

Pictures of Retail, Office, Special Purpose property located at 8 Celadon Dr, Beaufort, SC 29907 for lease - image #1
$1.68/SF/MO
8 Celadon Dr
Retail • Single tenant • 2250 SqFt

8 Celadon Dr Beaufort, SC 29907

Pictures of Special Purpose property located at 2139 N Main Street # L, Summerville, SC 29486 for lease - image #1
$15/SF/YR
2139 N Main Street # L
Special Purpose • Single tenant • 1,670 SqFt

2139 N Main Street # L Summerville, SC 29486

Pictures of Industrial, Special Purpose property located at 1507 Beckham St, West Columbia, SC 29169 for lease - image #1
$1.44/SF/MO
1507 Beckham
Industrial • Single tenant • 900 SqFt

1507 Beckham St West Columbia, SC 29169

Pictures of Industrial, Land, Special Purpose property located at 729 White Oak Dr, Johnsonville, SC 29555 for lease - image #1
$1 - $10,000/SF/MO
INDUSTRIAL VALUE ADD SWEAT EQUITY LEASE - THEN RENT
Industrial Value Add Sweat Equity Lease - Then Rent Inception 146,270 SF (AS IS) Tenant Fix Up

729 White Oak Dr Johnsonville, SC 29555

Pictures of Special Purpose property located at 1180 Bees Ferry Road # 103 #B-103, Johns Island, SC 29455 for lease - image #1
$39/SF/YR
1180 Bees Ferry Road # 103 #B-103
Special Purpose • Single tenant • 1,462 SqFt - 3,116 SqFt

1180 Bees Ferry Road # 103 #B-103 Johns Island, SC 29455

Pictures of Special Purpose, Office property located at 300 Henry Pl, Spartanburg, SC 29306 for lease - image #1
$11.50/SF/YR
300 Henry Place
Special Purpose • Single tenant • 6,480 SqFt

300 Henry Pl Spartanburg, SC 29306

Pictures of Special Purpose property located at 4762 Rivers Avenue # C, North Charleston, SC 29405 for lease - image #1
$38/SF/YR
4762 Rivers Avenue # C
Special Purpose • Single tenant • 350 SqFt

4762 Rivers Avenue # C North Charleston, SC 29405

Pictures of Special Purpose property located at 89 Hanover Street # 101, Charleston, SC 29403 for lease - image #1
$1/SF/YR
89 Hanover Street # 101
Special Purpose • Single tenant • 930 SqFt - 960 SqFt

89 Hanover Street # 101 Charleston, SC 29403

Pictures of Special Purpose property located at 229 King Street, Charleston, SC 29401 for lease - image #1
$75/SF/YR
229 King Street
Special Purpose • Single tenant • 3,740 SqFt

229 King Street Charleston, SC 29401

Pictures of Special Purpose property located at 413 Main Street S #Unit 1, New Ellenton, SC 29809 for lease - image #1
$1.57/SF/MO
413 Main Street S #Unit 1
Special Purpose • Single tenant • 510 SqFt

413 Main Street S #Unit 1 New Ellenton, SC 29809

Pictures of Retail, Office, Special Purpose property located at 804 Inlet Square Drive, Murrells Inlet, SC 29576 for lease - image #1
$17/SF/YR
Planters Market

804 Inlet Square Drive Murrells Inlet, SC 29576

Pictures of Office, Industrial, Special Purpose property located at 330 Wingo Heights Rd, Spartanburg, SC 29303 for lease - image #1
$7/SF/YR
330 E Wingo Heights Road, Spartanburg, SC
Warehouse I Office • Single tenant I 7,500 SF

330 Wingo Heights Rd Spartanburg, SC 29303

Pictures of Office, Special Purpose property located at 100 Corporate Boulevard, West Columbia, SC 29169 for lease - image #1
$15.55/SF/YR
100 Corporate Boulevard
Move-In Ready ±17,800 SF Office Building with Showroom

100 Corporate Boulevard West Columbia, SC 29169

Pictures of Retail, Office, Special Purpose property located at 5110 Fairfield Rd, Columbia, SC 29203 for lease - image #1
virtual tour
$11/SF/YR
Food Lion–Anchored Retail Center | Fairfield Rd
Food Lion–Anchored Retail & Medical Space • 3,600–14,208 SF

5110 Fairfield Rd Columbia, SC 29203

Pictures of Special Purpose property located at 511 Irby Street , Florence, SC 29501 for lease - image #1
$0.74/SF/MO
511 Irby Street
Special Purpose • Single tenant • 6,120 SqFt

511 Irby Street Florence, SC 29501

Pictures of Special Purpose property located at 401 2nd Loop Rd, Florence, SC 29505 for lease - image #1
$14/SF/MO
401 second Loop Rd. A and B
Special Purpose • Single tenant • 2,400 SqFt

401 2nd Loop Rd Florence, SC 29505

Pictures of Retail, Office, Special Purpose property located at 3598 SC-11, Travelers Rest, SC 29690 for lease - image #1
virtual tour
Undisclosed Rate
Offices on Eleven
Retail • 10 spaces available • 72 SqFt - 28,000 SqFt

3598 SC-11 Travelers Rest, SC 29690

Pictures of Special Purpose property located at 513 Red Bank Road # B, Goose Creek, SC 29445 for lease - image #1
$63.16/SF/YR
513 Red Bank Road # B
Special Purpose • Single tenant • 380 SqFt

513 Red Bank Road # B Goose Creek, SC 29445

Pictures of Special Purpose property located at 99 West Edge Street # 1100, Charleston, SC 29403 for lease - image #1
$30/SF/YR
99 West Edge Street # 1100
Special Purpose • Single tenant • 2,915 SqFt

99 West Edge Street # 1100 Charleston, SC 29403

Pictures of Special Purpose property located at 143 Berkeley Circle #103/104, Summerville, SC 29483 for lease - image #1
$35/SF/YR
143 Berkeley Circle #103/104
Special Purpose • Single tenant • 3,080 SqFt

143 Berkeley Circle #103/104 Summerville, SC 29483

Pictures of Retail, Special Purpose property located at 1050 Fording Island Road, Bluffton, SC 29910 for lease - image #1
$28/SF/YR
1050 Fording Island Road

1050 Fording Island Road Bluffton, SC 29910

Pictures of Special Purpose property located at 1135 St James Avenue Suite 101, Summerville, SC 29486 for lease - image #1
$32/SF/YR
1135 St James Avenue Suite 101
Special Purpose • Single tenant • 1,213 SqFt - 4,850 SqFt

1135 St James Avenue Suite 101 Summerville, SC 29486

Pictures of Special Purpose property located at 1135 St James Avenue Suite 103, Summerville, SC 29486 for lease - image #1
$32/SF/YR
1135 St James Avenue Suite 103
Special Purpose • Single tenant • 1,193 SqFt - 4,850 SqFt

1135 St James Avenue Suite 103 Summerville, SC 29486

Pictures of Industrial, Special Purpose property located at 2314 Air Park Road, North Charleston, SC 29406 for lease - image #1
$15.50/SF/YR
2314 Air Park Road
Industrial • Single tenant • 15,000 SqFt

2314 Air Park Road North Charleston, SC 29406

Pictures of Special Purpose, Retail, Office property located at Carolina Park Boulevard # 5 #Building B, Unit 5, Mount Pleasant, SC 29466 for lease - image #1
$36/SF/YR
Carolina Park Boulevard # 5 #Building B, Unit 5
Special Purpose • Single tenant • 1,400 SqFt - 7,200 SqFt

Carolina Park Boulevard # 5 #Building B, Unit 5 Mount Pleasant, SC 29466

Pictures of Special Purpose property located at Carolina Park Boulevard # 1 #Building A, Unit 1, Mount Pleasant, SC 29466 for lease - image #1
$33 - $36/SF/YR
Carolina Park Boulevard # 1 #Building A, Unit 1
Special Purpose • Single tenant • 1,405 SqFt - 8,481 SqFt

Carolina Park Boulevard # 1 #Building A, Unit 1 Mount Pleasant, SC 29466

Pictures of Special Purpose property located at 9140 Ocean Highway Unit 4, Pawleys Island, SC 29585 for lease - image #1
$16/SF/YR
9140 Ocean Highway Unit 4
Special Purpose • Single tenant • 1,400 SqFt

9140 Ocean Highway Unit 4 Pawleys Island, SC 29585

Pictures of Special Purpose property located at 386 E 5th North Street, Summerville, SC 29483 for lease - image #1
$35/SF/YR
386 E 5th North Street
Special Purpose • Single tenant • 6,392 SqFt

386 E 5th North Street Summerville, SC 29483

Pictures of Special Purpose property located at 545 Parkwood Estates Drive, Charleston, SC 29407 for lease - image #1
$30.50/SF/YR
545 Parkwood Estates Drive
Special Purpose • Single tenant • 1,655 SqFt

545 Parkwood Estates Drive Charleston, SC 29407

Pictures of Retail, Industrial, Special Purpose property located at 630 Hampshire Dr, Gaffney, SC 29341 for lease - image #1
$12.50/SF/YR
Retail/Service Building with Visibility from 85
Retail • Single tenant • 16,457 SqFt

630 Hampshire Dr Gaffney, SC 29341

Pictures of Industrial, Office, Special Purpose property located at 1559 Sam Rittenberg Blvd, Charleston, SC 29407 for lease - image #1
$20/SF/YR
1559 Sam Rittenberg Boulevard
Flex • Warehouse • 1,800 SqFt

1559 Sam Rittenberg Blvd Charleston, SC 29407

Pictures of Office, Industrial, Special Purpose property located at 6548 Ward Ave, Charleston, SC 29406 for lease - image #1
virtual tour
$19 - $25/SF/YR
Flex-Unit - Mixed-Use Warehouse Space in Charleston, SC
Office • 3 spaces available • 1,400 SqFt - 4,200 SqFt

6548 Ward Ave Charleston, SC 29406

Pictures of Office, Industrial, Special Purpose property located at 2666 South Lake Drive, Lexington, SC 29073 for lease - image #1
$9/SF/YR
2666 South Lake Drive
Building for Lease Hwy 6 and 302

2666 South Lake Drive Lexington, SC 29073

Pictures of Land, Special Purpose property located at 150 Cooper Rd, Piedmont, SC 29673 for lease - image #1
$5,000/Acre/MO
Cooper Rd @ Hwy 153
Land • Single tenant • 1 acre

150 Cooper Rd Piedmont, SC 29673

Results per page:

Nearby Special Purpose Spaces

Show Less

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591