

120 Salem Ave – Downtown Adaptive Reuse Opportunity
Spaces
Retail | Single tenant | 20,000 SqFt - 40,000 SqFt
Building description
120 SALEM AVE | ROANOKE, VA
Downtown Adaptive Reuse Opportunity | Power, Scale & Location
Property Highlights
32,000± SF across 2 stories + mezzanine, ideal for mixed-use redevelopment
Super Heavy Power: ~3 MW electrical capacity
High Load Capacity: 250 lbs/SF floors support lab, data, or production uses
Ceiling Heights: soaring 20–42 ft, perfect for creative or industrial volumes
Zoning: D-Downtown District – flexible for office, retail, hospitality, or residential
Enterprise Zone Incentives – state and local redevelopment tax credits available
Dock-High & Drive-In Loading for versatile logistics and production uses
Brick & Glass Façade with authentic industrial architecture
Mezzanine-ready structure for loft offices or event overlooks
Adjacent to City Skywalk and steps from civic, state, and federal buildings
Proximity to Virginia Tech Carilion & Fralin Biomedical Research Institute (˜1 mile)
Regional Access: Easy connection to I-581, Amtrak, Greenways, and Roanoke-Blacksburg Regional Airport
Development & Adaptive Reuse Potential
Creative Office Conversion: bright, open spaces with exposed materials and mezzanine lounges
Innovation or Research Hub: suitable for tech, data, or biotech operations
Brewery / Taproom Destination: indoor-outdoor capacity with an authentic industrial shell
Urban Loft Redevelopment: high-ceiling residential units with skyline views
Civic or Cultural Hub: event space, gallery, or nonprofit/education use
Location Advantages
In the heart of Roanoke’s urban core, surrounded by 60+ restaurants and shops
Walkable to municipal and healthcare campuses
Mountain and skyline views of the Blue Ridge from the upper levels
Regional Reach: 194 mi to Charlotte | 251 mi to Washington, DC | 403 mi to Philadelphia | 430 mi to Atlanta
Ideal For
Developers seeking adaptive reuse or mixed-use repositioning
Tech, creative, or biomedical tenants requiring power + proximity to Carilion & VT
Hospitality or brewery operators seeking iconic downtown architecture
Civic or institutional users expanding community-facing programs
Building highlights
±32,000 SF across two stories + mezzanine, ideal for adaptive reuse or mixed-use redevelopment
Massive power availability (~3 MW) and 250 lbs/SF floor loads for lab, tech, data, or production uses
20–42 ft ceiling heights with authentic brick-and-glass industrial architecture
D-Downtown zoning with flexibility for office, retail, hospitality, residential, or institutional uses
Enterprise Zone incentives with state and local redevelopment tax credits
Dock-high and drive-in loading; mezzanine-ready structure for loft offices or event space
Adjacent to the City Skywalk and minutes to Virginia Tech Carilion & Fralin Biomedical Research Institute
Strong downtown location with 60+ restaurants/shops nearby and easy access to I-581, Amtrak, and ROA Airport
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