1400 S Grand Ave, Los Angeles, CA 90015

Welcome to California Professional Center, a premier Class A medical office tower located at 1400 S Grand Avenue in the heart of Downtown Los Angeles’ dynamic South Park District. Positioned directly adjacent to Dignity Health – California Hospital Medical Center, this 8-story, ±77,946 SF building offers an unmatched opportunity for healthcare providers seeking a prestigious, hospital-adjacent location within one of the most medically and demographically active markets in Southern California.

Built in 1990 and meticulously maintained, the building features high-end finishes, expansive views of the city skyline, and a commanding presence at a key intersection. From the dramatic lobby entrance to the fully built-out suites with 12-foot ceilings, the property blends professionalism, comfort, and operational efficiency—tailored for specialists, surgical groups, outpatient services, diagnostic labs, and other high-traffic medical uses.

Tenants benefit from direct connectivity to the region’s premier inpatient and trauma care center, plus an established ecosystem of referral partners—including Keck Medicine, AIDS Healthcare Foundation, LabCorp, Synovation Medical Group, and multiple surgical centers—all operating within the building. With this built-in synergy, new tenants can plug into an existing patient flow and benefit from the credibility and foot traffic of a hospital campus without the overhead of hospital-owned real estate.

In addition to its healthcare pedigree, the building offers full-service property management, 24/7 security and access, a four-level covered parking structure, and excellent transit access via Metro and DASH lines. With on-site amenities including a ground-floor pharmacy and café access, the property delivers convenience for staff and patients alike.

This is more than just medical space—it’s a strategic location that enhances patient care, elevates your brand, and supports long-term practice growth in the heart of Los Angeles.