Sienna Medical Plaza
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Join MD Anderson | Class A Medical Office | Sienna | Hwy 6
Building description
Sienna Medical Plaza is a newly delivered, two-story Class A medical office building located on Highway 6 in Missouri City—at the front door of the Sienna master-planned community. Sienna’s official master plan materials cite a population nearing 40,000, providing a deep, affluent patient base and consistent daily traffic from rooftops to retail and services.
The entire 1st floor is leased to MD Anderson, immediately establishing this address as a healthcare destination and creating built-in credibility and referral synergy for complementary providers. Now leasing: the full 2nd floor (18,400 SF)—a contiguous, elevator-served medical floor plate ideal for specialty clinics, imaging, oncology support services, women’s health, therapy/rehab, lab users, or medical admin groups seeking adjacency to a premier anchor.
From an investment and leasing standpoint, this location sits in one of the most resilient growth engines in Greater Houston: Fort Bend County was among the top U.S. counties for numeric population gains in 2023, supporting long-term demand for healthcare and professional services. The surrounding Missouri City trade area also reflects strong purchasing power, with Census QuickFacts reporting median household income ~$94K (2020–2024, in 2024 dollars).
Building highlights
• Anchored by MD Anderson Cancer Center (Entire 1st Floor Leased)
• Rare Institutional-Quality Medical Asset in Sienna Corridor
• 18,400 SF Contiguous 2nd Floor – Divisible for Strategic Users
• Built-In Referral Synergy & Daily Patient Traffic
• Class A, Two-Story Purpose-Built Medical Construction
• Elevator-Served with Professional Healthcare Lobby
• Prominent Highway 6 Visibility & Access
• Positioned Within Rapidly Expanding Sienna Master-Planned Community
• Strong 4:1,000 Parking Ratio
• Efficient Floor Plate Ideal for Specialty & Clinical Layouts
• Designed for Imaging, Infusion, Oncology Support, Women’s Health & Specialty Care
• Institutional Image & Long-Term Corridor Stability
• Surrounded by Affluent Residential Growth & Retail Amenities
• Medical Identity Established from Day One
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