www.crexi.com - The Commercial Real Estate Exchange
For Lease
All Types 

Palmdale, CA Spaces for Lease

103 spaces
Pictures of Retail, Office property located at 2501-2505 E Palmdale Blvd., Palmdale, CA 93550 for lease - image #1
$1.50/SF/MO
25th Street Center
Retail • 4 spaces available • 1,100 SqFt - 2,200 SqFt

2501-2505 E Palmdale Blvd. Palmdale, CA 93550

Pictures of Retail, Land property located at 1233 Rancho Vista Blvd, Palmdale, CA 93551 for lease - image #1
Undisclosed Rate
Antelope Valley Mall
Retail • 4 spaces available • 1 acre - 2 acre

1233 Rancho Vista Blvd Palmdale, CA 93551

Pictures of Retail, Office, Industrial property located at 190 Sierra Ct  Palmdale CA 93550, Palmdale, CA 93550 for lease - image #1
$549 - $749/SF/MO
Sierra Hwy Plaza Palmdale
Retail • 2 spaces available • 100 SqFt - 3,500 SqFt

190 Sierra Ct Palmdale CA 93550 Palmdale, CA 93550

Pictures of Land property located at 525 W Ave P-4, Palmdale, CA 93551 for lease - image #1
Undisclosed Rate
525 West Avenue P-4
Land • Single tenant • 3 acre

525 W Ave P-4 Palmdale, CA 93551

Pictures of Office property located at 40015 Sierra Hwy, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
Sierra Gateway Bldg B
Office • 2 spaces available • 1,200 SqFt - 3,267 SqFt

40015 Sierra Hwy Palmdale, CA 93550

Pictures of Retail, Office, Restaurant property located at 2211-2361 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
Palmdale Place Commerce Center
Palmdale Place 2211-2361 E. Palmdale Blvd, Palmdale, CA 93550

2211-2361 E Palmdale Blvd Palmdale, CA 93550

INTELLIGENCE
Instantly evaluate properties and markets with confidence.
Analyze data, market trends, sales comps, demographics, and more.
Learn More
Pictures of Retail property located at 39178 10th St W, Palmdale, CA 93551 for lease - image #1
$2.50/SF/MO
Palmdale Marketplace - 39178 10th St. W.
Retail • 2 spaces available • 1,482 SqFt - 1,767 SqFt

39178 10th St W Palmdale, CA 93551

Pictures of Office property located at 650 Commerce Ave, Palmdale, CA 93551 for lease - image #1
$3.22 - $6/SF/MO
Venture Commerce Center
Office • 125 SqFt - 605 SqFt

650 Commerce Ave Palmdale, CA 93551

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Land, Industrial property located at Sierra Hwy, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
Palmdale Energy & Infrastructure Development Site
Land • 1 space available • 22 acre

Sierra Hwy Palmdale, CA 93550

Pictures of Industrial property located at 0 Avenue N, Palmdale, CA 93550 for lease - image #1
$3,000/SF/MO
0 Avenue N
Industrial • Single tenant • 363,010 SqFt

0 Avenue N Palmdale, CA 93550

Pictures of Industrial property located at NE of Sierra Hwy and E Ave M, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
Antelope Valley Commerce Center East
Industrial • 6 Buildings Available • 67,950 SF - 1,004,880 SF

NE of Sierra Hwy and E Ave M Palmdale, CA 93550

Pictures of Office property located at 1529 E. Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$2.10/SF/MO
1529 E. Palmdale Blvd
Office • 12 spaces available • 575 SqFt - 9,632 SqFt

1529 E. Palmdale Blvd Palmdale, CA 93550

Pictures of Retail property located at 2720 East Palmdale Boulevard, Palmdale, CA 93550 for lease - image #1
$1.35/SF/MO
Suite 112 off E Palmdale Blvd
Retail • Single tenant • 1,071 SqFt

2720 East Palmdale Boulevard Palmdale, CA 93550

Pictures of Retail, Industrial property located at 39006 20th St E, Palmdale, CA 93550 for lease - image #1
$2.50/SF/MO
39006 20th St E
Industrial • Single tenant • 4,800 SqFt

39006 20th St E Palmdale, CA 93550

Pictures of Office property located at 1543 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$1.50 - $1.75/SF/MO
Roy Business Park
Office • 3 spaces available • 162 SqFt - 1,494 SqFt

1543 E Palmdale Blvd Palmdale, CA 93550

Pictures of Retail property located at 2042 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$2 - $2.50/SF/MO
Town Center West
Retail • 3 spaces available • 1,731 SqFt - 7,000 SqFt

2042 E Palmdale Blvd Palmdale, CA 93550

Pictures of Retail property located at 38463 9th St E, Palmdale, CA 93550 for lease - image #1
$1.65/SF/MO
38463 9th St E, Palmdale CA 93550
Retail • 1 space available • 1,569 SqFt

38463 9th St E Palmdale, CA 93550

Pictures of Office property located at 40005 10th St W, Palmdale, CA 93551 for lease - image #1
$2.25 - $2.32/SF/MO
Palm West Plaza - 40005 10th St. W.
Office • 2 spaces available • 400 SqFt - 6,000 SqFt

40005 10th St W Palmdale, CA 93551

Pictures of Retail property located at 38360 20th St E, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
Former 99 Cent Only
Anchor Space available • 10,000 SqFt - 22,128 SqFt • Adjacent to Superior Grocers

38360 20th St E Palmdale, CA 93550

Pictures of Office property located at 38660 Medical Center Dr, Palmdale, CA 93551 for lease - image #1
Undisclosed Rate
Palmdale Regional Medical Center
Office • 6 spaces available • 2,130 SqFt - 6,747 SqFt

38660 Medical Center Dr Palmdale, CA 93551

Pictures of Retail property located at 1852 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$2.50/SF/MO
1852 East Palmdale
Retail • 1 space available • 680 SqFt

1852 E Palmdale Blvd Palmdale, CA 93550

Pictures of Retail property located at 422 W Avenue P, Palmdale, CA 93551 for lease - image #1
$2/SF/YR
Palmdale Promenade - 440-442 W. Rancho Vista Blvd.
Retail • 3 spaces available • 1,450 SqFt - 12,000 SqFt

422 W Avenue P Palmdale, CA 93551

Pictures of Retail property located at 202 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$29.40/SF/YR
6-Bay Auto Shop Next to In-N-Out
Retail • Single tenant • 3,057 SqFt

202 E Palmdale Blvd Palmdale, CA 93550

Pictures of Retail, Restaurant property located at 2162 East Palmdale Boulevard, Palmdale, CA 93550 for lease - image #1
video
$2.15/SF/MO
Restaurant Stand-Alone
+/- 6,000 sq.ft. restaurant building with a full liquor license.

2162 East Palmdale Boulevard Palmdale, CA 93550

Pictures of Retail property located at 4621 E Avenue S, Palmdale, CA 93552 for lease - image #1
video
$1 - $2.25/SF/MO
Park Plaza - 4621 E. Ave. S
Retail • 7 spaces available • 1,400 SqFt - 21,500 SqFt

4621 E Avenue S Palmdale, CA 93552

Pictures of Industrial property located at 39415 8th St E, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
39415 8th St E
Industrial • 380,410 SF • Sale or Lease

39415 8th St E Palmdale, CA 93550

Pictures of Retail, Office property located at 520-540 W Palmdale Blvd, Palmdale, CA 93551 for lease - image #1
$22.68/SF/YR
520-540 W Palmdale Blvd
Retail • 1 space available • 1,000 SqFt - 4,326 SqFt

520-540 W Palmdale Blvd Palmdale, CA 93551

Pictures of Land property located at Sierra Hwy, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
Industrial Land for Lease –Contractor Yard/Equipment Storage
Land • Single tenant • 5-10 acre

Sierra Hwy Palmdale, CA 93550

Pictures of Retail, Land property located at Sierra Highway & Pearblossom Highway, Palmdale, CA 93552 for lease - image #1
Undisclosed Rate
NEC Sierra Hwy & Pearblossom Hwy
Retail • 4 spaces available • 1,224 SqFt - 88,605 SqFt

Sierra Highway & Pearblossom Highway Palmdale, CA 93552

Pictures of Retail property located at Sierra Hwy, Lake Los Angeles, CA 93550 for lease - image #1
Undisclosed Rate
Sierra Hwy
Retail • 2 spaces available • 4 acre - 11 acre

Sierra Hwy Lake Los Angeles, CA 93550

Pictures of Special Purpose property located at 3833 East Ave R-12, Palmdale, CA 93550 for lease - image #1
$2.75/SF/MO
Former 6-Bed CLHF-Ready Congregate Living Health Facility
Special Purpose • Single tenant • 1,527 SqFt

3833 East Ave R-12 Palmdale, CA 93550

Pictures of Retail, Land property located at W Palmdale Blvd & 4th St, Palmdale, CA 93551 for lease - image #1
Undisclosed Rate
Entitled Hotel Development
110-Key Hotel Development Opportunity

W Palmdale Blvd & 4th St Palmdale, CA 93551

Pictures of Retail, Office property located at 3005 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$1.10/SF/MO
30th Street Center
Retail • 3 spaces available • 1,250 SqFt - 1,918 SqFt

3005 E Palmdale Blvd Palmdale, CA 93550

Pictures of Office property located at 39959 Sierra Hwy, Palmdale, CA 93550 for lease - image #1
Undisclosed Rate
Sierra Gateway Bldg A
Office • 2 spaces available • 1,520 SqFt - 5,512 SqFt

39959 Sierra Hwy Palmdale, CA 93550

Pictures of Industrial, Land, Special Purpose property located at Largo Vista Rd, Palmdale, CA 93591 for lease - image #1
$50 - $500/SF/MO
#5=9.62 AC | Truck Yard 4 Lease/Sale
9.62 AC Truck Storage Yard

Largo Vista Rd Palmdale, CA 93591

Pictures of Industrial, Land, Special Purpose property located at 39000 Clock Tower Plaza Dr E, Palmdale, CA 93550 for lease - image #1
$50 - $500/SF/MO
#1=1.10 AC | Truck Yard 4 Lease/Sale
1.10 AC Truck Storage Yard/Industrial • Single tenant

39000 Clock Tower Plaza Dr E Palmdale, CA 93550

Pictures of Retail property located at Swc Rancho Vista & 10th, Palmdale, CA 93551 for lease - image #1
Undisclosed Rate
Amargosa Commons
Retail • 2 spaces available • 1,882 SqFt - 3,028 SqFt

Swc Rancho Vista & 10th Palmdale, CA 93551

Pictures of Retail property located at 2720 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$1.50/SF/MO
Suite 101 adjacent to Palmdale Blvd
Retail • Single tenant • 1,100 SqFt

2720 E Palmdale Blvd Palmdale, CA 93550

Pictures of Retail, Office property located at 2140 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
video
$2.15/SF/MO
Towne Square Plaza
7,000 sq.ft. +/- Turn-Key Retail Space For Lease at The Towne Square Plaza

2140 E Palmdale Blvd Palmdale, CA 93550

Pictures of Retail property located at 2553 E Palmdale Blvd, Palmdale, CA 93550 for lease - image #1
$1.25 - $1.84/SF/MO
Garden Plaza
Retail • 4 spaces available • 900 SqFt - 2,000 SqFt

2553 E Palmdale Blvd Palmdale, CA 93550

Pictures of Office property located at 38425 20th St E, Palmdale, CA 93550 for lease - image #1
$1.50/SF/MO
Eastside Medical - 38429 20th St. E.
Office • 1 space available • 1,385 SqFt

38425 20th St E Palmdale, CA 93550

Pictures of Retail property located at 440 W Rancho Vista Blvd, Palmdale, CA 93551 for lease - image #1
$2/SF/MO
Palmdale Promenade - 440-442 W. Rancho Vista Blvd.
Retail • 3 spaces available • 1,450 SqFt - 12,000 SqFt

440 W Rancho Vista Blvd Palmdale, CA 93551

Pictures of Office property located at 1008 W Ave M-14, Palmdale, CA 93551 for lease - image #1
Undisclosed Rate
42155 11th St
Office • 1 space available • 3,000 SqFt - 24,600 SqFt

1008 W Ave M-14 Palmdale, CA 93551

...... 1

Nearby Spaces

Show Less

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591