www.crexi.com - The Commercial Real Estate Exchange
For Lease
Office 

Charleston Executive Office Spaces for Lease

128 spaces
Pictures of Office property located at 656 Ellis Oak Ave, Charleston, SC 29412 for lease - image #1
Undisclosed Rate
Ellis Oaks Office Park
Executive Office Space

656 Ellis Oak Ave Charleston, SC 29412

Pictures of Retail, Office property located at 2030 Wambaw Crk Rd, Charleston, SC 29492 for lease - image #1
$16 - $17/SF/YR
2030 Wambaw Creek Road
Retail • 2 spaces available • 1,437 SqFt - 7,118 SqFt

2030 Wambaw Crk Rd Charleston, SC 29492

Pictures of Office property located at 835 Savannah Hwy, Charleston, SC 29407 for lease - image #1
Undisclosed Rate
The Victory
Office • 4 spaces available • 96 SqFt

835 Savannah Hwy Charleston, SC 29407

Pictures of Retail, Office property located at 192 E Bay Street # 205, Charleston, SC 29401 for lease - image #1
Undisclosed Rate
192 E Bay Street # 205
Retail • Single tenant • 420 SqFt

192 E Bay Street # 205 Charleston, SC 29401

Pictures of Office, Industrial property located at 105 Wappoo Creek Drive # 2b, Charleston, SC 29412 for lease - image #1
$42.86/SF/YR
105 Wappoo Creek Drive # 2b
Office • Single tenant • 252 SqFt - 582 SqFt

105 Wappoo Creek Drive # 2b Charleston, SC 29412

Pictures of Office property located at 134 Meeting St, Charleston, SC 29401 for lease - image #1
Undisclosed Rate
134 Meeting St
Office • Single tenant • 1,109 SqFt

134 Meeting St Charleston, SC 29401

INTELLIGENCE
Instantly evaluate properties and markets with confidence.
Analyze data, market trends, sales comps, demographics, and more.
Learn More
Pictures of Retail, Office property located at 41 Simons Street, Charleston, SC 29403 for lease - image #1
$6.60/SF/MO
41 Simons Street - Suite 101
318sf first level office or creative suite

41 Simons Street Charleston, SC 29403

Pictures of Office property located at 234 Seven Farms Drive, Charleston, SC 29492 for lease - image #1
$60.77 - $64.71/SF/YR
Four Corners Plaza
Executive Suites for Lease

234 Seven Farms Drive Charleston, SC 29492

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Office property located at 40 Calhoun St, Charleston, SC 29401 for lease - image #1
$39.23 - $42.04/SF/YR
Charleston Gateway Campus
Executive Office Suites for lease

40 Calhoun St Charleston, SC 29401

Pictures of Office property located at 184 East Bay Street, Charleston, SC 29401 for lease - image #1
$41/SF/YR
184 East Bay Street
Office/Retail for Lease

184 East Bay Street Charleston, SC 29401

Pictures of Office property located at 521 and 525 Folly Road, Charleston, SC 29412 for lease - image #1
Undisclosed Rate
521 and 525 Folly Road
Office Space For Lease

521 and 525 Folly Road Charleston, SC 29412

Pictures of Office property located at 40 Calhoun Street # 250j, Charleston, SC 29401 for lease - image #1
$36.61/SF/YR
40 Calhoun Street # 250j
Executive Office Suite for lease

40 Calhoun Street # 250j Charleston, SC 29401

Pictures of Office property located at 180 E Bay Street, Charleston, SC 29401 for lease - image #1
$38/SF/YR
180 E Bay St - Second Floor
Office • 2 spaces available • 76 SqFt - 4,000 SqFt

180 E Bay Street Charleston, SC 29401

Pictures of Office property located at 125-C Wappoo Creek Drive, Charleston, SC 29412 for lease - image #1
$20 - $23/SF/YR
125-C Wappoo Creek Drive
Office • 3 spaces available • 660 SqFt - 2,200 SqFt

125-C Wappoo Creek Drive Charleston, SC 29412

Pictures of Office property located at 1013 Physicians Drive, Charleston, SC 29414 for lease - image #1
$28/SF/YR
1013 Physicians Drive
Office • 1 space available • 2,160 SqFt - 4,320 SqFt

1013 Physicians Drive Charleston, SC 29414

Pictures of Office property located at 65 Fairchild St, Charleston, SC 29492 for lease - image #1
video
Undisclosed Rate
65 Fairchild St
Office • 6,948 SqFt - 25,570 SqFt

65 Fairchild St Charleston, SC 29492

Pictures of Office property located at 40 Calhoun Street Suite 205 #Suite 205-South, Charleston, SC 29401 for lease - image #1
$38/SF/YR
Charleston Gateway Center
Charleston Gateway Office Space for lease

40 Calhoun Street Suite 205 #Suite 205-South Charleston, SC 29401

Pictures of Office, Restaurant property located at 463 King St, Charleston, SC 29403 for lease - image #1
$34/SF/YR
463 King Street
Office • 1 space available • 3,204 SqFt

463 King St Charleston, SC 29403

Pictures of Office property located at 125 Fairchild Street 2nd Floor Charleston South Carolina, Charleston, SC 29492 for lease - image #1
$10.51 - $12.50/SF/MO
Flexible workspace in SC, Charleston - Fairchild Street. Book a tour & get info
Flexible workspace in SC, Charleston - Fairchild Street. Book a tour & get info

125 Fairchild Street 2nd Floor Charleston South Carolina Charleston, SC 29492

Pictures of Office property located at 215 Benefitfocus Way #3rd Floor, Charleston, SC 29492 for lease - image #1
$34.50/SF/YR
215 Benefitfocus Way #3rd Floor
Office • Single tenant • 15,000 SqFt - 72,900 SqFt

215 Benefitfocus Way #3rd Floor Charleston, SC 29492

Pictures of Office property located at 174 Meeting St, Charleston, SC 29401 for lease - image #1
Undisclosed Rate
174 Meeting St
Office • Single tenant • 15,039 SqFt

174 Meeting St Charleston, SC 29401

Pictures of Office property located at 720 Magnolia Rd, Charleston, SC 29407 for lease - image #1
$22.77/SF/YR
720 Magnolia Road - The School House
Professional office space for lease

720 Magnolia Rd Charleston, SC 29407

Pictures of Office property located at 65 FAIRCHILD ST, CHARLESTON, SC 29492 for lease - image #1
$41/SF/MO
65 FAIRCHILD ST CHARLESTON SC 29492

65 FAIRCHILD ST CHARLESTON, SC 29492

Pictures of Office property located at 115 Fairchild Street, Charleston, SC 29492 for lease - image #1
$29.95 - $32/SF/YR
The Landing
Office • 5 spaces available • 2,157 SqFt - 15,324 SqFt

115 Fairchild Street Charleston, SC 29492

Pictures of Office property located at 706 Orleans Road, Charleston, SC 29407 for lease - image #1
$18/SF/YR
706 Orleans Road
Office • 1 space available • 107 SqFt - 1,000 SqFt

706 Orleans Road Charleston, SC 29407

Pictures of Office property located at 125 G Wappoo Creek, Charleston, SC 29412 for lease - image #1
Undisclosed Rate
125 Wappoo Creek - Executive Office Lease
Office • 2 spaces available • 60 SqFt - 104 SqFt

125 G Wappoo Creek Charleston, SC 29412

Pictures of Office property located at 40 Calhoun Street # 250e, Charleston, SC 29401 for lease - image #1
$40.29/SF/YR
40 Calhoun Street # 250e
Executive Office Suite for lease

40 Calhoun Street # 250e Charleston, SC 29401

Pictures of Office property located at 1064 Gardner Road # 104, Charleston, SC 29407 for lease - image #1
$24 - $28/SF/YR
1064 Gardner Road # 104
Office • Single tenant • 962 SqFt

1064 Gardner Road # 104 Charleston, SC 29407

Pictures of Office property located at 211 King St, Charleston, SC 29401 for lease - image #1
$4.17 - $50.09/SF/YR
211 King Street, 102 & 103
Second Floor Executive Office Space in Downtown Charleston

211 King St Charleston, SC 29401

Pictures of Office property located at 170 Meeting Street, 1st, 2nd and 3rd Floors, Charleston, SC 29401 for lease - image #1
$0.79 - $12.76/SF/MO
Flexible workspace in Downtown Charleston. Book a tour & get info
Flexible workspace in Downtown Charleston. Book a tour & get info

170 Meeting Street, 1st, 2nd and 3rd Floors Charleston, SC 29401

Pictures of Office property located at 174 E East Bay Street # C, Charleston, SC 29401 for lease - image #1
$24.50/SF/YR
174 E East Bay Street # C
Office • Single tenant • 1,703 SqFt

174 E East Bay Street # C Charleston, SC 29401

Pictures of Office property located at 115 Fairchild Street Suite 100 Charleston South Carolina, Charleston, SC 29492 for lease - image #1
$0.67 - $11.84/SF/MO
Flexible workspace in SC, Charleston - 115 Fairchild Street. Book a tour & get info
Flexible workspace in SC, Charleston - 115 Fairchild Street. Book a tour & get info

115 Fairchild Street Suite 100 Charleston South Carolina Charleston, SC 29492

Pictures of Office property located at 8439 Palmetto Commerce Pkwy, Awendaw, SC 29401 for lease - image #1
Undisclosed Rate
8439 Palmetto Commerce Parkway
Office • Single tenant • 15,467 SqFt

8439 Palmetto Commerce Pkwy Awendaw, SC 29401

Pictures of Office, Industrial property located at 1950 Belgrade Ave, Charleston, SC 29407 for lease - image #1
$22 - $24/SF/YR
1950 Belgrade Ave
Office

1950 Belgrade Ave Charleston, SC 29407

Pictures of Office property located at 215 Benefitfocus Way, Charleston, SC 29492 for lease - image #1
Undisclosed Rate
215 Benefitfocus Way
Office • 7,500 SqFt - 145,800 SqFt

215 Benefitfocus Way Charleston, SC 29492

Pictures of Office property located at 174 Meeting St, Charleston, SC 29401 for lease - image #1
$42/SF/YR
174 Meeting Street
Office • Single tenant • 14,502 SqFt

174 Meeting St Charleston, SC 29401

Pictures of Office property located at 263 King St, Charleston, SC 29401 for lease - image #1
$24/SF/YR
Built-out King Street Office Space
Office • Single tenant • 2,200 - 4,400 SqFt

263 King St Charleston, SC 29401

Pictures of Office property located at 215 Benefitfocus Way #4th Floor, Charleston, SC 29492 for lease - image #1
$34.50/SF/YR
215 Benefitfocus Way #4th Floor
Office • Single tenant • 15,000 SqFt - 72,900 SqFt

215 Benefitfocus Way #4th Floor Charleston, SC 29492

Pictures of Office property located at 215 Benefitfocus Way, Charleston, SC 29492 for lease - image #1
Undisclosed Rate
215 Benefitfocus Way
Office • 8,500 SqFt - 36,450 SqFt

215 Benefitfocus Way Charleston, SC 29492

Pictures of Office property located at 40 Calhoun Street # 250i, Charleston, SC 29401 for lease - image #1
$39.83/SF/YR
40 Calhoun Street # 250i
Executive Office Suites for lease

40 Calhoun Street # 250i Charleston, SC 29401

Pictures of Office, Industrial property located at 2000 Sam Rittenberg Boulevard # 3001, Charleston, SC 29407 for lease - image #1
$28.50/SF/YR
Harrell Square
Office • Single tenant • 2,304 SqFt

2000 Sam Rittenberg Boulevard # 3001 Charleston, SC 29407

Pictures of Office property located at 2000 Sam Rittenberg Blvd, Charleston, SC 29407 for lease - image #1
$26.50/SF/YR
Harrell Square
Office • 1 space available • 4,064 SqFt

2000 Sam Rittenberg Blvd Charleston, SC 29407

Pictures of Office property located at 656 Ellis Oak Avenue # 113, Charleston, SC 29412 for lease - image #1
$118/SF/YR
656 Ellis Oak Avenue # 113
Office • Single tenant • 137 SqFt

656 Ellis Oak Avenue # 113 Charleston, SC 29412

Pictures of Office property located at 41 Simons Street, Charleston, SC 29403 for lease - image #1
$6.38/SF/MO
41 Simons Street - Suite 206
548 SF private office or creative suite

41 Simons Street Charleston, SC 29403

Pictures of Office property located at 41 Simons Street, Charleston, SC 29403 for lease - image #1
$6.34/SF/MO
41 Simons Street - Suite 219
264 SF private office or studio suite

41 Simons Street Charleston, SC 29403

Pictures of Retail, Office property located at 41 Simons Street, Charleston, SC 29403 for lease - image #1
$7.11/SF/MO
41 Simons Street - Suite 104
Suite 104 - 197 SF suite

41 Simons Street Charleston, SC 29403

Pictures of Retail, Office property located at 151 MEETING ST, CHARLESTON, SC 29401-2207 for lease - image #1
$1/SF/YR
151 Meeting Street, Suite 200

151 MEETING ST CHARLESTON, SC 29401-2207

Pictures of Retail, Office property located at 320 Broad St, Charleston, SC 29401 for lease - image #1
$110.09 - $196.22/SF/YR
Ashley Artisan Suites at The Jasper
Start Your Business at Ashley Artisan Suites in Downtown Charleston

320 Broad St Charleston, SC 29401

Pictures of Office property located at 645 Meeting Street, Charleston, SC 29403 for lease - image #1
Undisclosed Rate
Innovation Center
Office • 1 space available • 1 SqFt

645 Meeting Street Charleston, SC 29403

Pictures of Retail, Office, Restaurant property located at 100 Calhoun St, Charleston, SC 29401 for lease - image #1
$43/SF/YR
100 Calhoun Street
Retail • 1 space available • 5,000 SqFt - 9,675 SqFt

100 Calhoun St Charleston, SC 29401

Pictures of Office property located at 2 S Park Cir, Charleston, SC 29407 for lease - image #1
$29/SF/YR
South Park Plaza
Office • 1 space available • 3,843 SqFt - 9,275 SqFt

2 S Park Cir Charleston, SC 29407

Pictures of Office property located at 1064 Gardner Rd, Charleston, SC 29407 for lease - image #1
$24 - $28/SF/YR
Garden View Office Park
Office • 5 spaces available • 800 SqFt - 2,652 SqFt

1064 Gardner Rd Charleston, SC 29407

Pictures of Office property located at 525 E Bay St, Charleston, SC 29403 for lease - image #1
$39 - $44/SF/YR
525 East Bay Street
Office • 2 spaces available • 1,901 SqFt - 14,515 SqFt

525 E Bay St Charleston, SC 29403

Pictures of Office property located at 40 Calhoun Street # 250h, Charleston, SC 29401 for lease - image #1
$39.23/SF/YR
40 Calhoun Street # 250h
Executive Office Suite for lease

40 Calhoun Street # 250h Charleston, SC 29401

Pictures of Office property located at 16 Broad St, Charleston, SC 29401 for lease - image #1
$5/SF/MO
16 Broad Street
Office • 1 space available • 128 SqFt - 5,874 SqFt

16 Broad St Charleston, SC 29401

Pictures of Office property located at 635 E Bay St, Charleston, SC 29403 for lease - image #1
$27.81/SF/MO
Sublease Office Available- Short Term Lease Available
Office • Single tenant • 920 SqFt

635 E Bay St Charleston, SC 29403

Pictures of Retail, Office property located at 41 Simons Street, Charleston, SC 29403 for lease - image #1
$6.45/SF/MO
41 Simons Street - Suite 204
349 SF second level office or creative suite

41 Simons Street Charleston, SC 29403

Pictures of Office property located at 1951 Clements Ferry Rd, Charleston, SC 29492 for lease - image #1
$22/SF/YR
Former Physical Therapy 1951 Clements Ferry Road
Office • 1 space available • 2,500 SqFt

1951 Clements Ferry Rd Charleston, SC 29492

...... 1

Executive Office Spaces by Market

Show Less

Spaces by Type

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591