www.crexi.com - The Commercial Real Estate Exchange
For Lease
All Types 

Charleston County Spaces for Lease

290 spaces
Pictures of Retail property located at 1749 Sam Rittenberg Blvd, Charleston, SC 29407 for lease - image #1
$30/SF/YR
1749 Sam Rittenberg Blvd
Retail • Single tenant • 4,900 SqFt

1749 Sam Rittenberg Blvd Charleston, SC 29407

Pictures of Office property located at 656 Ellis Oak Ave, Charleston, SC 29412 for lease - image #1
Undisclosed Rate
Ellis Oaks Office Park
Executive Office Space

656 Ellis Oak Ave Charleston, SC 29412

Pictures of Industrial property located at 4269-G Crosspoint Dr, Ladson, SC 29456 for lease - image #1
Undisclosed Rate
Crosspoint V
Industrial • 2 spaces available • 39,000 SqFt - 52,000 SqFt

4269-G Crosspoint Dr Ladson, SC 29456

Pictures of Industrial property located at 4279-J Crosspoint Dr, Ladson, SC 29456 for lease - image #1
Undisclosed Rate
Crosspoint VI
Industrial • 1 space available • 26,000 SqFt

4279-J Crosspoint Dr Ladson, SC 29456

Pictures of Retail, Office, Industrial property located at 98 Peytons Way, Summerville, SC 29483 for lease - image #1
Undisclosed Rate
98 Peytons Way Unit A
Retail • Single tenant • 2,500 SqFt

98 Peytons Way Summerville, SC 29483

Pictures of Retail, Office property located at 5335 Dorchester Rd, North Charleston, SC 29418 for lease - image #1
$16.50/SF/YR
Evanston Plaza
Retail • 2 spaces available • 1,390 SqFt

5335 Dorchester Rd North Charleston, SC 29418

INTELLIGENCE
Instantly evaluate properties and markets with confidence.
Analyze data, market trends, sales comps, demographics, and more.
Learn More
Pictures of Office, Industrial property located at 7171 Bryhawke Cir, North Charleston, SC 29418 for lease - image #1
Undisclosed Rate
7171 Bryhawke Cir, unit 300
Office • Single tenant • 2,000 SqFt

7171 Bryhawke Cir North Charleston, SC 29418

Pictures of Office property located at 3227 Walter Drive, Johns Island, SC 29455 for lease - image #1
$23/SF/YR
Johns Island Office/Medical Space - 3227 Walter Drive Ste C1
Medical/Office Space • 2000 Square Feet

3227 Walter Drive Johns Island, SC 29455

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Office, Special Purpose property located at 180 Spring St, Charleston, SC 29403 for lease - image #1
virtual tour
$1,250/SF/MO
180 Spring Street
Office • 1 space available • 400 SqFt - 550 SqFt

180 Spring St Charleston, SC 29403

Pictures of Industrial property located at 1949 Dulsey Road, Charleston, SC 29407 for lease - image #1
$18/SF/YR
1949 Dulsey Road, Unit 201

1949 Dulsey Road Charleston, SC 29407

Pictures of Retail, Office property located at 41 Simons Street, Charleston, SC 29403 for lease - image #1
$6.60/SF/MO
41 Simons Street - Suite 101
318sf first level office or creative suite

41 Simons Street Charleston, SC 29403

Pictures of Restaurant, Retail property located at Maybank Hwy, Johns Island, SC 29455 for lease - image #1
Undisclosed Rate
Fenwick Alley
Now Leasing - New Retail Shopping Center - Fenwick Alley - Johns Island

Maybank Hwy Johns Island, SC 29455

Pictures of Office property located at 2113 Middle St, Sullivan's Island, SC 29482 for lease - image #1
$1/SF/YR
The Jetties
Office • Single tenant • 100 SqFt - 6,600 SqFt

2113 Middle St Sullivan's Island, SC 29482

Pictures of Retail, Office, Restaurant property located at 1031 & 1039 Hwy 41, Mount Pleasant, SC 29466 for lease - image #1
$28/SF/YR
Station 41
Retail • 3 spaces available • 1,120 SqFt - 1,340 SqFt

1031 & 1039 Hwy 41 Mount Pleasant, SC 29466

Pictures of Retail property located at 852 Orleans Rd, Charleston, SC 29407 for lease - image #1
Undisclosed Rate
852 Orleans Rd
Retail • 1 space available • 1,658 SqFt

852 Orleans Rd Charleston, SC 29407

Pictures of Office property located at 1300 Hospital Dr, Mt Pleasant, SC 29464 for lease - image #1
video
Undisclosed Rate
East Cooper Medical Center
Office • Multiple Suites Available • 1,564 sq. ft. - 7,502 sq. ft.

1300 Hospital Dr Mt Pleasant, SC 29464

Pictures of Office property located at 880 Johnnie Dodds Blvd, Mt Pleasant, SC 29464 for lease - image #1
$28/SF/YR
880 Johnnie Dodds Blvd
Office • 1 space available • 2,400 SqFt

880 Johnnie Dodds Blvd Mt Pleasant, SC 29464

Pictures of Retail property located at 102 President St, Charleston, SC 29403 for lease - image #1
$40 - $45/SF/YR
Presidents Place
Retail • 2 spaces available • 1,962 SqFt - 2,075 SqFt

102 President St Charleston, SC 29403

Pictures of Retail, Office property located at 4360 Corporate Rd, North Charleston, SC 29405 for lease - image #1
$22.50/SF/YR
4360 Corporate Road
Retail • 5 spaces available • 4,324 SqFt - 16,737 SqFt

4360 Corporate Rd North Charleston, SC 29405

Pictures of Retail property located at 3861 West Ashley Circle, Charleston, SC 29414 for lease - image #1
$33/SF/YR
3861 W Ashley Circle Building E, Suite 110
Retail spaces for Lease

3861 West Ashley Circle Charleston, SC 29414

Pictures of Industrial, Office property located at 3245 Benchmark Dr, Ladson, SC 29456 for lease - image #1
$6.50/Acre/YR
3245 Benchmark Drive
60,000sf Freestanding Warehouse on 4.33 acres

3245 Benchmark Dr Ladson, SC 29456

Pictures of Retail property located at 880 Whipple Road, Mt Pleasant, SC 29464 for lease - image #1
$26/SF/YR
880 Whipple Road
Former Attorney Space For Lease

880 Whipple Road Mt Pleasant, SC 29464

Pictures of Retail property located at 6165 Savannah Hwy, Ravenel, SC 29470 for lease - image #1
$22/SF/YR
6165 Savannah Hwy
Retail • Single tenant • 2,000 SqFt

6165 Savannah Hwy Ravenel, SC 29470

Pictures of Office property located at 7301 Rivers Avenue, North Charleston, SC 29406 for lease - image #1
$24/SF/YR
7301 Rivers Avenue Suite 248
1,210 SF Office Space Available in North Charleston!

7301 Rivers Avenue North Charleston, SC 29406

Pictures of Industrial property located at 912 Autonomous Dr, Ridgeville, SC 29472 for lease - image #1
$7.75/SF/YR
Camp Hall Campus 8,Camp Hall C
Industrial • Single tenant • 183,757 SqFt

912 Autonomous Dr Ridgeville, SC 29472

Pictures of Industrial property located at 1125 Redwood Materials Dr, Ridgeville, SC 29472 for lease - image #1
$6.35/SF/YR
Camp Hall Campus 8 Camp Hall A
Industrial • Single tenant • 971,302 SqFt

1125 Redwood Materials Dr Ridgeville, SC 29472

Pictures of Office property located at 521 and 525 Folly Road, Charleston, SC 29412 for lease - image #1
Undisclosed Rate
521 and 525 Folly Road
Office Space For Lease

521 and 525 Folly Road Charleston, SC 29412

Pictures of Office property located at 800 Johnnie Dodds Blvd, Mt Pleasant, SC 29464 for lease - image #1
Undisclosed Rate
Executive Offices on Johnnie Dodds Mt. Pleasant
Office Space For Lease

800 Johnnie Dodds Blvd Mt Pleasant, SC 29464

Pictures of Industrial property located at 9035-G Sightline Dr, Ladson, SC 29456 for lease - image #1
Undisclosed Rate
Crosspoint X
Industrial • Single tenant • 31,000 SqFt

9035-G Sightline Dr Ladson, SC 29456

Pictures of Land property located at 1945 Jacksonville Rd, North Charleston, SC 29405 for lease - image #1
virtual tour
$1,000/Acre/MO
Jacksonville B-2 Commercial Land For Lease
Land • 2 spaces available • 1 acre

1945 Jacksonville Rd North Charleston, SC 29405

Pictures of Retail property located at 1500 Parklawn Dr, Charleston, SC 29414 for lease - image #1
Undisclosed Rate
1500 Parklawn Dr
Retail • Single tenant • 379,673 SqFt

1500 Parklawn Dr Charleston, SC 29414

Pictures of Retail property located at 9 Linguard St, Charleston, SC 29401 for lease - image #1
Undisclosed Rate
9 Linguard
Retail • Mixed-Use Development • 3,000 SqFt

9 Linguard St Charleston, SC 29401

Pictures of Office property located at 211 King Street, Charleston, SC 29401 for lease - image #1
$35/SF/YR
211 King Street
Sub-Lease/2,638 SQ FT - 8 Private Offices

211 King Street Charleston, SC 29401

Pictures of Retail property located at 966 Houston Northcutt Blvd, Mount Pleasant, SC 29464 for lease - image #1
Undisclosed Rate
Bridgewater Center
Retail • Single tenant • 2,750 SqFt

966 Houston Northcutt Blvd Mount Pleasant, SC 29464

Pictures of Office property located at 814 US-17, Mount Pleasant, SC 29464 for lease - image #1
$34/SF/YR
New, First-Gen Office Space in Mt. Pleasant 29464
Office • Single tenant • 2,756 SqFt

814 US-17 Mount Pleasant, SC 29464

Pictures of Retail, Restaurant, Special Purpose property located at 3863 W Ashley Circle, Charleston, SC 29414 for lease - image #1
$33/SF/YR
West Ashley Circle Shopping Center
Retail Spaces for Lease

3863 W Ashley Circle Charleston, SC 29414

Pictures of Office, Restaurant property located at 463 King St, Charleston, SC 29403 for lease - image #1
$34/SF/YR
463 King Street
Office • 1 space available • 3,204 SqFt

463 King St Charleston, SC 29403

Pictures of Office, Industrial property located at 4509 Savannah Hwy, Ravenel, SC 29470 for lease - image #1
$15/SF/YR
South Stono Business Park
Office • 2 spaces available • 4,533 SqFt

4509 Savannah Hwy Ravenel, SC 29470

Pictures of Retail property located at 3861 West Ashley Circle, Charleston, SC 29414 for lease - image #1
$33/SF/YR
3861 W Ashley Circle Building E, Suite 100
Retail Spaces for lease

3861 West Ashley Circle Charleston, SC 29414

Pictures of Retail, Office property located at 3316 Ashley Phosphate Road, North Charleston, SC 29418 for lease - image #1
$17.72/SF/YR
3316 Ashley Phosphate Road #12
Retail/Office space for SubLease

3316 Ashley Phosphate Road North Charleston, SC 29418

Pictures of Retail, Office property located at 756 Saint Andrews Boulevard, Charleston, SC 29407 for lease - image #1
$20/SF/YR
Highly Visible Office Space with Parking in West Ashley
1,437 SF with Parking

756 Saint Andrews Boulevard Charleston, SC 29407

Pictures of Office property located at 1501 Belle Isle Avenue, Mt Pleasant, SC 29464 for lease - image #1
$1/SF/YR
1501 Belle Isle, Suite 200
1501 Belle Isle Avenue, Suite 200 • Mount Pleasant, SC - Available for Sublease • 6,008 SF

1501 Belle Isle Avenue Mt Pleasant, SC 29464

Pictures of Retail, Office, Restaurant property located at 838 Morrison Dr, Charleston, SC 29403 for lease - image #1
$46/SF/YR
Morrison Yard
Retail • 3 spaces available • 1,360 SqFt - 6,786 SqFt

838 Morrison Dr Charleston, SC 29403

Pictures of Industrial property located at 7240 Cross Park Drive, North Charleston, SC 29418 for lease - image #1
Undisclosed Rate
7240 Cross Park Drive
Industrial

7240 Cross Park Drive North Charleston, SC 29418

Pictures of Retail, Office property located at 3791 Betsy Kerrison Parkway, Bldg 5, Johns Island, SC 29455 for lease - image #1
$55/SF/YR
South Island Market - Wellness, Fitness, Medical - Building 5
Retail • 2 spaces available • 2,487 SqFt

3791 Betsy Kerrison Parkway, Bldg 5 Johns Island, SC 29455

Pictures of Retail property located at 8780 Rivers Ave, North Charleston, SC 29406 for lease - image #1
$20/SF/YR
Otranto Plaza
Retail • 1 space available • 2,800 SqFt

8780 Rivers Ave North Charleston, SC 29406

Pictures of Office property located at 255 E Bay St, Charleston, SC 29401 for lease - image #1
$35/SF/YR
255 East Bay Street
Office • Single tenant • 4,730 SqFt

255 E Bay St Charleston, SC 29401

Pictures of Office property located at 4900 O'Hear Ave, Charleston, SC 29405 for lease - image #1
Undisclosed Rate
Venture X - Garco Mill
Office • 83 spaces available • 54 SqFt - 1,400 SqFt

4900 O'Hear Ave Charleston, SC 29405

Pictures of Office property located at 184 East Bay Street, Charleston, SC 29401 for lease - image #1
$41/SF/YR
184 East Bay Street
Office/Retail for Lease

184 East Bay Street Charleston, SC 29401

Pictures of Industrial property located at 4540 Rivers Ave, North Charleston, SC 29405 for lease - image #1
$20/SF/YR
4540 Rivers Ave
Industrial • 1 space available • 2,267 SqFt - 10,000 SqFt

4540 Rivers Ave North Charleston, SC 29405

Pictures of Office property located at 125 G Wappoo Creek, Charleston, SC 29412 for lease - image #1
Undisclosed Rate
125 Wappoo Creek - Executive Office Lease
Workspace Office Space For Lease

125 G Wappoo Creek Charleston, SC 29412

Pictures of Industrial property located at 9028-A Palmetto Commerce Pkwy., Ladson, SC 29456 for lease - image #1
$10.75/SF/YR
Crosspoint IX
Industrial • Single tenant • 40,500 SqFt

9028-A Palmetto Commerce Pkwy. Ladson, SC 29456

Pictures of Industrial property located at 4250-A Crosspoint Dr, Ladson, SC 29456 for lease - image #1
$8.75/SF/YR
Crosspoint XI
Industrial • Single tenant • 157,407 SqFt

4250-A Crosspoint Dr Ladson, SC 29456

Pictures of Office property located at 3660 Bessemer Rd 101, Mount Pleasant, SC 29466 for lease - image #1
$30/SF/YR
3660 Bessemer Rd 101
Office • Single tenant • 1,510 SqFt

3660 Bessemer Rd 101 Mount Pleasant, SC 29466

Pictures of Retail property located at 1035 Johnnie Dodds Blvd, Mount Pleasant, SC 29464 for lease - image #1
Undisclosed Rate
Fairmount Landing
Retail • 9 spaces available • 155 SqFt - 6,413 SqFt

1035 Johnnie Dodds Blvd Mount Pleasant, SC 29464

Pictures of Office property located at 8439 Palmetto Commerce Pkwy, Awendaw, SC 29401 for lease - image #1
Undisclosed Rate
8439 Palmetto Commerce Parkway
Office • Single tenant • 15,467 SqFt

8439 Palmetto Commerce Pkwy Awendaw, SC 29401

Pictures of Retail, Office property located at 106 W Hudson Ave Unit 2A, Folly Beach, SC 29439 for lease - image #1
$41/SF/MO
106 W. Hudson Unit 2A
Retail • Single tenant • 820 SqFt

106 W Hudson Ave Unit 2A Folly Beach, SC 29439

Pictures of Office property located at 1671 Belle Isle Avenue, Mount Pleasant, SC 29464 for lease - image #1
$32/SF/YR
1671 Belle Isle Avenue
Office • 3 spaces available • 2,227 SqFt - 8,582 SqFt

1671 Belle Isle Avenue Mount Pleasant, SC 29464

Pictures of Retail property located at 1739 Maybank Highway, Charleston, SC 29412 for lease - image #1
$38/SF/YR
James Island Shopping Center
Retail • 2 spaces available • 900 SqFt - 3,200 SqFt

1739 Maybank Highway Charleston, SC 29412

Pictures of Retail, Restaurant property located at 51 George St, Charleston, SC 29401 for lease - image #1
$45/SF/YR
51 George Street
Retail • 2 spaces available • 1,611 SqFt - 2,030 SqFt

51 George St Charleston, SC 29401

Results per page:

Nearby Spaces

Show Less

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591