www.crexi.com - The Commercial Real Estate Exchange
For Lease
Office 

Lease Commercial Real Estate and Property

1,210 spaces
Pictures of Office property located at 10 S Academy St, Greenville, SC 29601 for lease - image #1
$25.50/SF/YR
10 S. Academy Street
Office • 2 spaces available • 5,196 SqFt - 14,719 SqFt

10 S Academy St Greenville, SC 29601

Pictures of Office property located at 102 Commons Blvd, Powdersville, SC 29673 for lease - image #1
$15/SF/YR
102 Commons Blvd
Office Space just off I-85

102 Commons Blvd Powdersville, SC 29673

Pictures of Office property located at 301 N Main St, Greenville, SC 29601 for lease - image #1
$25/SF/YR
The Daniel Building
Office • 19 spaces available • 844 SqFt - 58,975 SqFt

301 N Main St Greenville, SC 29601

Pictures of Office property located at 330 Pelham Rd, Greenville, SC 29615 for lease - image #1
$21/SF/YR
330 Pelham Road
Prime Office space with excellent visibility

330 Pelham Rd Greenville, SC 29615

Pictures of Retail, Office, Restaurant property located at 1031 & 1039 Hwy 41, Mount Pleasant, SC 29466 for lease - image #1
$28/SF/YR
Station 41
Retail • 3 spaces available • 1,120 SqFt - 1,340 SqFt

1031 & 1039 Hwy 41 Mount Pleasant, SC 29466

Pictures of Office property located at 124 Verdae Blvd, Greenville, SC 29607 for lease - image #1
$26/SF/YR
Bonaventure II
Office • 1 space available • 4,146 SqFt - 8,995 SqFt

124 Verdae Blvd Greenville, SC 29607

INTELLIGENCE
Instantly evaluate properties and markets with confidence.
Analyze data, market trends, sales comps, demographics, and more.
Learn More
Pictures of Office property located at 200 Oakland Ave, Rock Hill, SC 29730 for lease - image #1
$16.15/SF/YR
The Oakland Building
Office • 1 space available • 1,300 SqFt

200 Oakland Ave Rock Hill, SC 29730

Pictures of Retail, Office property located at 1023 Fernwood-Glendale Rd, Spartanburg, SC 29307 for lease - image #1
$16/SF/YR
1023 Fernwood -Glendale Rd
Retail • 3 spaces available • 1,800 SqFt - 5,800 SqFt

1023 Fernwood-Glendale Rd Spartanburg, SC 29307

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Retail, Office, Restaurant property located at 550 S Church St, Spartanburg, SC 29306 for lease - image #1
$7 - $14/SF/YR
550 S Church Street
Retail • 1,400 SqFt - 17,073 SqFt

550 S Church St Spartanburg, SC 29306

Pictures of Office property located at 995 Old York Rd, Chester, SC 29706 for lease - image #1
Undisclosed Rate
995 Old York Road
For Lease • Office/Flex Space

995 Old York Rd Chester, SC 29706

Pictures of Retail, Office property located at 14322 E Wade Hampton Blvd, Greer, SC 29651 for lease - image #1
$21.75/SF/YR
Wade Hampton East Bldg (Site 428)
Retail • 1 space available • 800 SqFt - 1,200 SqFt

14322 E Wade Hampton Blvd Greer, SC 29651

Pictures of Office property located at 656 Ellis Oak Ave, Charleston, SC 29412 for lease - image #1
Undisclosed Rate
Ellis Oaks Office Park
Executive Office Space

656 Ellis Oak Ave Charleston, SC 29412

Pictures of Office property located at Edgewater Pkwy, Indian Land, SC 29707 for lease - image #1
Undisclosed Rate
Edgewater Medical/Office Building I
Office • 1 space available • 2,200 SqFt - 15,000 SqFt

Edgewater Pkwy Indian Land, SC 29707

Pictures of Office property located at 00 Edgewater Pkwy, Indian Land, SC 29707 for lease - image #1
Undisclosed Rate
Edgewater Medical/Office Building II
Medical Office - 2,200 sq. ft. - 30,000 sq. ft.

00 Edgewater Pkwy Indian Land, SC 29707

Pictures of Office property located at Edgewater Pkwy, Indian Land, SC 29707 for lease - image #1
Undisclosed Rate
Edgewater Medical/Office Building III
Office • 1 space available • 2,200 SqFt - 30,000 SqFt

Edgewater Pkwy Indian Land, SC 29707

Pictures of Restaurant, Office, Special Purpose property located at 504 Main St, North Myrtle Beach, SC 29582 for lease - image #1
Undisclosed Rate
5,000+/- SF Building on Main Street (Duplex)
Retail • Subdividable • 2,500 to 5,000 SqFt

504 Main St North Myrtle Beach, SC 29582

Pictures of Office property located at 620 W Evans St, Florence, SC 29501 for lease - image #1
$18/SF/MO
620 W Evans Street - Executive Office
Office • Single tenant • 3,000 SqFt

620 W Evans St Florence, SC 29501

Pictures of Office property located at 885 Gold Hill Rd, Fort Mill, SC 29708 for lease - image #1
$20 - $100/SF/MO
Venture X Fort Mill
NEW COWORKING SPACE • CLASS A OFFICE • 4 SPACES AVAILABLE • GOLD HILL ROAD

885 Gold Hill Rd Fort Mill, SC 29708

Pictures of Office, Industrial property located at 4900 US-501, Myrtle Beach, SC 29579 for lease - image #1
$11 - $18/SF/YR
10,000- 40,936 Divisible Flex Space/Warehouse on Hwy 501
Office • 4 spaces available • 7,346 SqFt - 40,936 SqFt

4900 US-501 Myrtle Beach, SC 29579

Pictures of Office property located at 1523 Sunset Blvd., West Columbia, SC 29169 for lease - image #1
$15/SF/YR
1523 Sunset Blvd
Office • 1 space available • 2,095 SqFt

1523 Sunset Blvd. West Columbia, SC 29169

Pictures of Office property located at 2141 Enterprise Dr, Florence, SC 29501 for lease - image #1
$17.50/SF/YR
2141 Enterprise Drive
Office • ±10,395 RSF

2141 Enterprise Dr Florence, SC 29501

Pictures of Office property located at 47 Airpark Ct, Greenville, SC 29607 for lease - image #1
$17/SF/YR
Premier Office Suites at 47 Airpark Ct
Office • Single tenant • 3,633 SqFt

47 Airpark Ct Greenville, SC 29607

Pictures of Retail, Office property located at 2 W Washington St, Greenville, SC 29601 for lease - image #1
Undisclosed Rate
Greenville ONE
Retail • 1 space available • 5,696 SqFt - 20,700 SqFt

2 W Washington St Greenville, SC 29601

Pictures of Office property located at 122 Riverwalk Blvd, Ridgeland, SC 29936 for lease - image #1
Undisclosed Rate
122 Riverwalk Boulevard
For Sublease: ±2,600 SF Office Space • Ridgeland, SC

122 Riverwalk Blvd Ridgeland, SC 29936

Pictures of Retail, Office, Restaurant property located at 8241 Pinellas Dr, Bluffton, SC 29910 for lease - image #1
$30/SF/YR
8241 Pinellas Dr
Retail / Restaurant for Lease • Bluffton SC

8241 Pinellas Dr Bluffton, SC 29910

Pictures of Retail, Office property located at 512 E Main St, Spartanburg, SC 29302 for lease - image #1
$15/SF/YR
512 E Main St
Retail • Single tenant • 2,046 SqFt

512 E Main St Spartanburg, SC 29302

Pictures of Retail, Office property located at 4360 Corporate Rd, North Charleston, SC 29405 for lease - image #1
$22.50/SF/YR
4360 Corporate Road
Retail • 5 spaces available • 4,324 SqFt - 16,737 SqFt

4360 Corporate Rd North Charleston, SC 29405

Pictures of Office property located at 835 Savannah Hwy, Charleston, SC 29407 for lease - image #1
Undisclosed Rate
The Victory
Office • 4 spaces available • 96 SqFt

835 Savannah Hwy Charleston, SC 29407

Pictures of Office property located at 110 Wildewood Park Dr, Columbia, SC 29223 for lease - image #1
$17.25 - $18.75/SF/YR
110 Wildewood Park Drive
Office • 3 spaces available • 478 SqFt - 2,158 SqFt

110 Wildewood Park Dr Columbia, SC 29223

Pictures of Office property located at 930 Richland St, Columbia, SC 29201 for lease - image #1
$25/SF/YR
930 Richland St
Office • 1 space available • 2,500 SqFt

930 Richland St Columbia, SC 29201

Pictures of Retail, Office, Industrial property located at 1618 Airport Blvd, West Columbia, SC 29169 for lease - image #1
$6 - $14.50/SF/YR
Airport Square
Airport Square

1618 Airport Blvd West Columbia, SC 29169

Pictures of Retail, Office property located at 3401 Forest Dr, Columbia, SC 29204 for lease - image #1
$15.75/SF/YR
3401 Forest Drive
Retail • 1 space available • 2,681 SqFt

3401 Forest Dr Columbia, SC 29204

Pictures of Retail, Office, Industrial property located at 1974 Carolina Pl, Fort Mill, SC 29708 for lease - image #1
Undisclosed Rate
1974 Carolina Place Dr
Retail • 5 spaces available • 220 SqFt - 4,000 SqFt

1974 Carolina Pl Fort Mill, SC 29708

Pictures of Office, Industrial property located at 2315 Prosperity Way, Florence, SC 29501 for lease - image #1
Undisclosed Rate
2315 Prosperity Way
Office • 2 spaces available • 2,000 SqFt - 7,119 SqFt

2315 Prosperity Way Florence, SC 29501

Pictures of Retail, Office, Restaurant property located at 8636 Old State Rd, Holly Hill, SC 29059 for lease - image #1
$12 - $15/SF/YR
8636 Old State Road
Retail • 5 spaces available • 549 SqFt - 2,509 SqFt

8636 Old State Rd Holly Hill, SC 29059

Pictures of Retail, Office property located at 408 E Main St, Spartanburg, SC 29302 for lease - image #1
$15.75/SF/YR
408 E. Main Street
Retail • 1 space available • 700 SqFt - 2,425 SqFt

408 E Main St Spartanburg, SC 29302

Pictures of Office property located at 23 Main St, Hilton Head Island, SC 29926 for lease - image #1
$26/SF/YR
101A Palmetto Office Suites
Office • 1 space available • 750 SqFt

23 Main St Hilton Head Island, SC 29926

Pictures of Office property located at 1245 Rosemont Dr, Fort Mill, SC 29707 for lease - image #1
Undisclosed Rate
Rosemont Park
Office • Executive Office • Light Medical

1245 Rosemont Dr Fort Mill, SC 29707

Pictures of Office property located at 7410 Northside Drive # 240, North Charleston, SC 29420 for lease - image #1
$22/SF/YR
7410 Northside Drive # 240
Office • Single tenant • 2,441 SqFt - 7,958 SqFt

7410 Northside Drive # 240 North Charleston, SC 29420

Pictures of Office property located at 1441 Main St, Columbia, SC 29201 for lease - image #1
Undisclosed Rate
1441 Main
Class A Office Space for Lease at 1441 Main • Downtown Columbia

1441 Main St Columbia, SC 29201

Pictures of Office property located at 4000 S. Faber Place Drive, Suite 300, Charleston, North Charleston, SC 29405 for lease - image #1
$1.11 - $11.08/SF/MO
Flexible workspace in Faber Center. Book a tour & get info
Flexible workspace in Faber Center. Book a tour & get info

4000 S. Faber Place Drive, Suite 300, Charleston North Charleston, SC 29405

Pictures of Office property located at 121 Professional Lane, Pawleys Island, SC 29585 for lease - image #1
$17/SF/YR
121 Professional Lane - Unit B
1500 Sq Ft Office Space

121 Professional Lane Pawleys Island, SC 29585

Pictures of Office property located at 220 North Main Street, Suite 500, Greenville, SC 29601 for lease - image #1
$0.73 - $11.27/SF/MO
Flexible workspace in NOMA Tower. Book a tour & get info
Flexible workspace in NOMA Tower. Book a tour & get info

220 North Main Street, Suite 500 Greenville, SC 29601

Pictures of Office property located at 900 Trail Ridge Rd, Aiken, SC 29803 for lease - image #1
$0.36 - $6.58/SF/MO
Flexible workspace in SC, Aiken – Trail Ridge. Book a tour & get info
Flexible workspace in SC, Aiken – Trail Ridge. Book a tour & get info

900 Trail Ridge Rd Aiken, SC 29803

Pictures of Office property located at 208 West Hampton Avenue, Sumter, SC 29150 for lease - image #1
$0.54 - $5.94/SF/MO
Flexible workspace in SC, Sumter - West Hampton Avenue. Book a tour & get info
Flexible workspace in SC, Sumter - West Hampton Avenue. Book a tour & get info

208 West Hampton Avenue Sumter, SC 29150

Pictures of Office property located at 140 Stoneridge Drive Suite 430 Columbia South Carolina, Columbia, SC 29210 for lease - image #1
$1 - $11.53/SF/MO
Flexible workspace in SC, Columbia - Stoneridge Drive. Book a tour & get info
Flexible workspace in SC, Columbia - Stoneridge Drive. Book a tour & get info

140 Stoneridge Drive Suite 430 Columbia South Carolina Columbia, SC 29210

Pictures of Office property located at 234 Seven Farms Drive, Charleston, SC 29492 for lease - image #1
$60.77 - $64.71/SF/YR
Four Corners Plaza
Executive Suites for Lease

234 Seven Farms Drive Charleston, SC 29492

Pictures of Retail, Office, Industrial property located at 98 Peytons Way, Summerville, SC 29483 for lease - image #1
Undisclosed Rate
98 Peytons Way Unit A
Retail • Single tenant • 2,500 SqFt

98 Peytons Way Summerville, SC 29483

Pictures of Office, Industrial property located at 9403 Hwy 78 # 201, Ladson, SC 29456 for lease - image #1
$25/SF/YR
9403 Hwy 78 # 201
Office • Single tenant • 2,635 SqFt

9403 Hwy 78 # 201 Ladson, SC 29456

Pictures of Office, Industrial property located at 7171 Bryhawke Cir, North Charleston, SC 29418 for lease - image #1
Undisclosed Rate
7171 Bryhawke Cir, unit 300
Office • Single tenant • 2,000 SqFt

7171 Bryhawke Cir North Charleston, SC 29418

Pictures of Office property located at 10 State Road S-7-50, Bluffton, SC 29909 for lease - image #1
$2.10 - $5.50/SF/MO
Buildings 400 Suite 403
Unique Park Like Setting

10 State Road S-7-50 Bluffton, SC 29909

Pictures of Retail, Office, Special Purpose property located at 882 E Main St, Spartanburg, SC 29302 for lease - image #1
Undisclosed Rate
882 E Main St - DOWNTOWN SPARTANBURG
Retail • Single tenant • 1,820 SqFt

882 E Main St Spartanburg, SC 29302

Pictures of Office, Special Purpose property located at 1323 Celebration Blvd, Florence, SC 29501 for lease - image #1
virtual tour
$20 - $25/SF/YR
1323 Celebration Blvd
Office • 1 space available • 12,000 SqFt - 37,000 SqFt

1323 Celebration Blvd Florence, SC 29501

Pictures of Office, Special Purpose property located at 12019 Ocean Hwy, Pawleys Island, SC 29585 for lease - image #1
$3,250/SF/MO
Pawley's Place
Office • 1,800 SqFt

12019 Ocean Hwy Pawleys Island, SC 29585

Pictures of Retail, Office property located at 900, 910, 986 Knox Abbott Dr., Cayce, SC 29033 for lease - image #1
$16 - $20/SF/YR
900, 910, 986 Knox Abbott Dr.
Retail • 3 spaces available • 800 SqFt - 3,000 SqFt

900, 910, 986 Knox Abbott Dr. Cayce, SC 29033

Pictures of Office property located at 1400 Browning Rd, Columbia, SC 29210 for lease - image #1
$20.75 - $22/SF/YR
Crown Pointe
Office • 2 spaces available • 2,581 SqFt - 4,185 SqFt

1400 Browning Rd Columbia, SC 29210

Pictures of Office, Special Purpose property located at 1051 Johnnie Dodds Blvd, Mt Pleasant, SC 29464 for lease - image #1
virtual tour
$2.83/SF/MO
Juliana Clinics and Studios
Office • 1 space available • 1,654 SqFt

1051 Johnnie Dodds Blvd Mt Pleasant, SC 29464

Pictures of Office property located at 904 Montague Ave, Greenwood, SC 29649 for lease - image #1
virtual tour
$1.72/SF/MO
Montague Office Space
Prime Professional Office Space Available at 904 Montague Ave – Greenwood, SC

904 Montague Ave Greenwood, SC 29649

Pictures of Retail, Office property located at 440 Old Trolley Rd, Summerville, SC 29485 for lease - image #1
$28/SF/YR
440-F Old Trolley Road
Retail • Single tenant • 1,900 SqFt

440 Old Trolley Rd Summerville, SC 29485

Pictures of Office property located at 401 W Cheves St, Florence, SC 29501 for lease - image #1
$12.44/SF/YR
401 W. Cheves Street
Office • Downtown Florence, SC

401 W Cheves St Florence, SC 29501

Executive Office Spaces by Market

Show Less

Spaces by Type

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591