www.crexi.com - The Commercial Real Estate Exchange
For Lease
All Types 

Spartanburg County Spaces for Lease

148 spaces
Pictures of Land property located at 1000 Asheville Hwy, Spartanburg, SC 29303 for lease - image #1
Undisclosed Rate
Land for Lease on Asheville Hwy
Land • Single tenant

1000 Asheville Hwy Spartanburg, SC 29303

Pictures of Industrial property located at 1050 Canaan Rd, Roebuck, SC 29376 for lease - image #1
$7/SF/YR
1050 Canaan Road
Industrial • Single tenant • 17,600 SqFt

1050 Canaan Rd Roebuck, SC 29376

Pictures of Land property located at 201 Giles Dr, Boiling Springs, SC 29316 for lease - image #1
$3,000/Acre/MO
201 Giles Dr
Land • Single tenant • 1 acre

201 Giles Dr Boiling Springs, SC 29316

Pictures of Retail property located at 1802 Drayton Rd, Spartanburg, SC 29333 for lease - image #1
$19/SF/YR
Second Generation Restaurant Space | Drayton Mills
Second Generation Restaurant Space • Drayton Mills Marketplace

1802 Drayton Rd Spartanburg, SC 29333

Pictures of Industrial property located at 1560 International Dr, Spartanburg, SC 29303 for lease - image #1
$7/SF/YR
Warehouse/Industrial Building
Industrial • Single tenant • 30,000 SqFt

1560 International Dr Spartanburg, SC 29303

Pictures of Industrial property located at 316 Business Pkwy, Greer, SC 29651 for lease - image #1
$14/SF/YR
316 Business Parkway
Industrial • 1 space available • 2,500 SqFt

316 Business Pkwy Greer, SC 29651

INTELLIGENCE
Instantly evaluate properties and markets with confidence.
Analyze data, market trends, sales comps, demographics, and more.
Learn More
Pictures of Land property located at 220 W Lanford St, Spartanburg, SC 29302 for lease - image #1
$4,000/Acre/MO
220 W Lanford Street
Land • Single tenant • 4 acre

220 W Lanford St Spartanburg, SC 29302

Pictures of Retail, Office, Special Purpose property located at 882 E Main St, Spartanburg, SC 29302 for lease - image #1
Undisclosed Rate
882 E Main St - DOWNTOWN SPARTANBURG
Retail • Single tenant • 1,820 SqFt

882 E Main St Spartanburg, SC 29302

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Industrial property located at 110 War Birds Blvd, Spartanburg, SC 29306 for lease - image #1
$7 - $12/SF/YR
110 WAR BIRDS INDUSTRIAL PARK
Industrial • Single tenant • 12,000 SqFt

110 War Birds Blvd Spartanburg, SC 29306

Pictures of Retail property located at 780 John B White Sr Blvd, Spartanburg, SC 29306 for lease - image #1
Undisclosed Rate
780 John B White Sr Blvd
Retail • Single tenant • 2,800 SqFt

780 John B White Sr Blvd Spartanburg, SC 29306

Pictures of Retail, Office, Special Purpose property located at 1215 Boiling Springs Road, Spartanburg, SC 29303 for lease - image #1
$10/SF/YR
1215 Boiling Springs Road
Office/Retail Space on Boiling Springs Rd

1215 Boiling Springs Road Spartanburg, SC 29303

Pictures of Office property located at 189 South Converse Street, Spartanburg, SC 29306 for lease - image #1
$7.18/SF/YR
189 South Converse Street
Prime Downtown Office Space with Parking

189 South Converse Street Spartanburg, SC 29306

Pictures of Industrial property located at 440 Southport Commerce Blvd, Spartanburg, SC 29306 for lease - image #1
video
$12/SF/YR
440 Southport Commerce Blvd
Industrial • Single tenant • 6,800 SqFt

440 Southport Commerce Blvd Spartanburg, SC 29306

Pictures of Retail, Office property located at 14322 E Wade Hampton Blvd, Greer, SC 29651 for lease - image #1
$21.75/SF/YR
Wade Hampton East Bldg (Site 428)
Retail • 1 space available • 800 SqFt - 1,200 SqFt

14322 E Wade Hampton Blvd Greer, SC 29651

Pictures of Retail, Industrial property located at 150 E Blackstock Rd, Spartanburg, SC 29302 for lease - image #1
$15/SF/YR
150 E Blackstock Rd
Retail • Single tenant • 9,000 SqFt

150 E Blackstock Rd Spartanburg, SC 29302

Pictures of Retail, Restaurant property located at 1675 E Main St, Duncan, SC 29334 for lease - image #1
$35/SF/YR
Salsaritas
Retail • 1 space available • 3,000 SqFt

1675 E Main St Duncan, SC 29334

Pictures of Office, Industrial, Special Purpose property located at 280 National Avenue, Spartanburg, SC 29303 for lease - image #1
$5.25/SF/YR
±62,000 SF Office/Industrial Space with Heavy Power Off I-26
±62,000 SF Office/Industrial Space with Heavy Power Off I-26

280 National Avenue Spartanburg, SC 29303

Pictures of Industrial, Land, Special Purpose property located at 00 National Avenue, Spartanburg, SC 29303 for lease - image #1
$3,000/Acre/YR
00 National Avenue
±8 Acre Industrial Outdoor Storage (IOS) Space Off I-26

00 National Avenue Spartanburg, SC 29303

Pictures of Land, Special Purpose property located at 1549 GSP Dr, Greer, SC 29651 for lease - image #1
Undisclosed Rate
Greenville - Spartanburg Airport - Tract I
Land • Single tenant • 69 acre

1549 GSP Dr Greer, SC 29651

Pictures of Retail, Land property located at E Wade Hampton Blvd & Pine Ridge Rd, Duncan, SC 29365 for lease - image #1
Undisclosed Rate
E Wade Hampton Blvd & Pine Ridge Rd
Retail • 2 spaces available • 10,500 SqFt

E Wade Hampton Blvd & Pine Ridge Rd Duncan, SC 29365

Pictures of Retail property located at 2199 Southport Rd, Spartanburg, SC 29306 for lease - image #1
Undisclosed Rate
Cedar Springs Crossing
Retail • 7 spaces available • 1,163 SqFt - 60,984 SqFt

2199 Southport Rd Spartanburg, SC 29306

Pictures of Industrial property located at 570 Commerce Pk Dr, Greer, SC 29651 for lease - image #1
Undisclosed Rate
Global Commerce Park - Building IV
Industrial • 1 space available • 182,000 SqFt

570 Commerce Pk Dr Greer, SC 29651

Pictures of Industrial property located at 120 East Victor Hill Road, Duncan, SC 29334 for lease - image #1
Undisclosed Rate
120 E Victor Hill Road
Industrial • 1 space available • 12,000 SqFt

120 East Victor Hill Road Duncan, SC 29334

Pictures of Retail, Office property located at 120 W St John St, Spartanburg, SC 29306 for lease - image #1
$22.50/SF/YR
120 W. St. John
Retail • Single tenant • 3,500 SqFt

120 W St John St Spartanburg, SC 29306

Pictures of Land property located at 153 Fortis Dr, Duncan, SC 29334 for lease - image #1
$4,000/Acre/MO
153 Fortis Drive
Land • Single tenant • 4 acre

153 Fortis Dr Duncan, SC 29334

Pictures of Industrial property located at 925 Berry Shoals Rd, Duncan, SC 29334 for lease - image #1
$8.50/SF/YR
925B Berry Shoals Road
Industrial • Single tenant • 28,000 SqFt

925 Berry Shoals Rd Duncan, SC 29334

Pictures of Retail, Restaurant property located at 8565 Fairforest Road, Spartanburg, SC 29303 for lease - image #1
$1,500/SF/YR
Fast point
Great retail location with thousands of cars daily

8565 Fairforest Road Spartanburg, SC 29303

Pictures of Industrial property located at 2362 S Pine St, Spartanburg, SC 29302 for lease - image #1
$6.76/SF/YR
2362 South Pine Street
Industrial • Single tenant • 20,790 SqFt

2362 S Pine St Spartanburg, SC 29302

Pictures of Retail, Restaurant, Special Purpose property located at 209 S Main St, Woodruff, SC 29388 for lease - image #1
$1.60/SF/MO
209 S Main St
Retail • Single tenant • 1,250 SqFt

209 S Main St Woodruff, SC 29388

Pictures of Retail, Restaurant property located at 138 S Main St, Woodruff, SC 29388 for lease - image #1
Undisclosed Rate
138-140 S. Main Street, Woodruff, SC 29388
Historic Woodruff Redevelopment Opportunity

138 S Main St Woodruff, SC 29388

Pictures of Industrial property located at 1101 Syphrit Rd, Wellford, SC 29385 for lease - image #1
Undisclosed Rate
Syphrit - Building D
Industrial • 9 spaces available • 11,970 SqFt - 27,400 SqFt

1101 Syphrit Rd Wellford, SC 29385

Pictures of Industrial property located at 296 Giles Drive, Boiling Springs, SC 29316 for lease - image #1
Undisclosed Rate
296 Giles Drive
Flex • Single Tenant • 5,000 SqFt

296 Giles Drive Boiling Springs, SC 29316

Pictures of Retail, Office, Special Purpose property located at 792 John B White Sr Boulevard, Spartanburg, SC 29306 for lease - image #1
$19/SF/YR
792 John B White Sr Boulevard
High-Visibility, Move-In Ready Office Space in the Heart of Spartanburg’s Growth Corridor

792 John B White Sr Boulevard Spartanburg, SC 29306

Pictures of Retail, Industrial property located at 409 State Road S-42-3106, Spartanburg, SC 29303 for lease - image #1
$13/SF/YR
3,000 SF | Industrial Property for Lease
3,000 SF Industrial Flex Space

409 State Road S-42-3106 Spartanburg, SC 29303

Pictures of Office property located at 1802 Drayton Road, Spartanburg, SC 29307 for lease - image #1
$16/SF/YR
Drayton Mills Marketplace office/creative space for lease
Drayton Mills Marketplace • Creative Offices for Lease

1802 Drayton Road Spartanburg, SC 29307

Pictures of Retail property located at 229 Charlotte Hwy, Lyman, SC 29365 for lease - image #1
$30/SF/MO
229 Charlotte Hwy
±1,250 - 2,500 SF Prime Retail Space

229 Charlotte Hwy Lyman, SC 29365

Pictures of Industrial property located at 3121 Old Furnace Rd, Boiling Springs, SC 29316 for lease - image #1
video
$10/SF/YR
Old Furnace Warehouse
Industrial • Single tenant • 5,000 SqFt

3121 Old Furnace Rd Boiling Springs, SC 29316

Pictures of Office property located at 101 N Pine St, Spartanburg, SC 29302 for lease - image #1
Undisclosed Rate
101 N Pine Street
Office • 1 space available • 759 SqFt

101 N Pine St Spartanburg, SC 29302

Pictures of Retail property located at 1752 E Main St, Spartanburg, SC 29307 for lease - image #1
Undisclosed Rate
1752 E. Main Street, Spartanburg, SC
Retail • Single tenant • 1,584 SqFt

1752 E Main St Spartanburg, SC 29307

Pictures of Retail, Land property located at 1391 W O. Ezell Blvd, Spartanburg, SC 29301 for lease - image #1
Undisclosed Rate
1391 W.O. Ezell Blvd, Spartanburg, SC
1.26-Acre Retail Development Site with High Visibility along US Hwy 29

1391 W O. Ezell Blvd Spartanburg, SC 29301

Pictures of Office property located at 236 Union Street, Spartanburg, SC 29302 for lease - image #1
$10/SF/MO
236 Union Street
±23,331 SF OFFICE/FLEX SPACE AVAILABLE FOR LEASE

236 Union Street Spartanburg, SC 29302

Pictures of Retail, Industrial property located at 729 S Church St, Spartanburg, SC 29306 for lease - image #1
$5.75 - $7/SF/YR
729 S Church St. Former Pepsi Bottling Plant
Retail • 1 space available • 7,000 SqFt - 74,490 SqFt

729 S Church St Spartanburg, SC 29306

Pictures of Office property located at 301 N Pine St, Spartanburg, SC 29302 for lease - image #1
$16/SF/YR
301 N. Pine Street
Office • 1 space available • 1,200 SqFt

301 N Pine St Spartanburg, SC 29302

Pictures of Industrial property located at 1101 Syphrit Rd, Wellford, SC 29385 for lease - image #1
Undisclosed Rate
Syphrit - Building A
Industrial • 6 spaces available • 2,615 SqFt - 11,000 SqFt

1101 Syphrit Rd Wellford, SC 29385

Pictures of Industrial property located at 501 Southport Rd, Spartanburg, SC 29301 for lease - image #1
Undisclosed Rate
501 Southport Road
Industrial • Single tenant • 12,125 SqFt

501 Southport Rd Spartanburg, SC 29301

Pictures of Industrial property located at 160 Lincoln School Road, Spartanburg, SC 29301 for lease - image #1
$5/SF/YR
160 Lincoln School Road
Industrial • 1 space available • 85,839 SqFt

160 Lincoln School Road Spartanburg, SC 29301

Pictures of Office, Industrial property located at 190 Old Roebuck Rd, Moore, SC 29369 for lease - image #1
$5.25/SF/YR
190 Old Roebuck Rd
Office • 1 space available • 26,782 SqFt

190 Old Roebuck Rd Moore, SC 29369

Pictures of Retail, Industrial property located at 807 W. O. Ezell Boulevard, Spartanburg, SC 29301 for lease - image #1
$14.77/SF/YR
803 W. O. Ezell Boulevard

807 W. O. Ezell Boulevard Spartanburg, SC 29301

Pictures of Retail, Office property located at 1447 Asheville Highway, Spartanburg, SC 29303 for lease - image #1
$14 - $17/SF/YR
1447 Asheville Highway
Retail • Single tenant • 2,200 SqFt - 10,000 SqFt

1447 Asheville Highway Spartanburg, SC 29303

Pictures of Office property located at 130 Dillon Dr, Spartanburg, SC 29307 for lease - image #1
$20/SF/YR
130 Dillon Drive
Office • 1 space available • 4,015 SqFt

130 Dillon Dr Spartanburg, SC 29307

Pictures of Industrial property located at 2355 South Carolina 101, Greer, SC 29651 for lease - image #1
Undisclosed Rate
2355 South Carolina Highway 101
Flex space: ±3,000 to 12,000 available

2355 South Carolina 101 Greer, SC 29651

Pictures of Land property located at 5975 US-221, Roebuck, SC 29376 for lease - image #1
$120,000/Acre/YR
3+/- Acres at Dorman Crossing
Land • Single tenant • 3 acre

5975 US-221 Roebuck, SC 29376

Pictures of Retail, Land property located at 3420 Boiling Springs Rd, Boiling Springs, SC 29316 for lease - image #1
Undisclosed Rate
Retail Build to Suit or Land Lease
Retail • Single tenant • 4,021 SqFt

3420 Boiling Springs Rd Boiling Springs, SC 29316

Pictures of Office property located at 607 Crown Pointe, Duncan, SC 29334 for lease - image #1
$20/SF/YR
Office Space With Garage and Large Lot
Excellent Location, Nice Office Space, Garage and Fenced Area

607 Crown Pointe Duncan, SC 29334

Pictures of Industrial, Retail property located at 107 Chinquepin Ln, Spartanburg, SC 29303 for lease - image #1
Undisclosed Rate
Build to Suit Opportunity, Excellent Location off 585
Industrial • Single tenant • 4 acre

107 Chinquepin Ln Spartanburg, SC 29303

Pictures of Industrial property located at 813 Tom Cat LN, Spartanburg, SC 29307 for lease - image #1
$6.85/SF/YR
813 Tom Cat Lane

813 Tom Cat LN Spartanburg, SC 29307

Pictures of Land property located at 592 Brockman McClimon Rd, Greer, SC 29651 for lease - image #1
Undisclosed Rate
Greenville - Spartanburg Airport - Tract G
Land • Single tenant • 250 acre

592 Brockman McClimon Rd Greer, SC 29651

Pictures of Industrial property located at 200 Herald Journal Blvd, Spartanburg, SC 29303 for lease - image #1
Undisclosed Rate
200 Herald Journal Blvd
Industrial • Single tenant • 55,119 SqFt

200 Herald Journal Blvd Spartanburg, SC 29303

Pictures of Retail, Restaurant property located at 2600 E Main St, Spartanburg, SC 29307 for lease - image #1
$26 - $30/SF/YR
±1,569 - 8,331 SF Retail / Office Suites
New Construction Retail/Office • 4 Suites Available • ±1,569 – 8,331 SF • Hwy 29, Spartanburg SC

2600 E Main St Spartanburg, SC 29307

Pictures of Retail property located at 1548 E Main St, Duncan, SC 29334 for lease - image #1
Undisclosed Rate
1548 E Main St
Retail • Single tenant • 1,581 SqFt

1548 E Main St Duncan, SC 29334

Results per page:

Nearby Spaces

Show Less

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591