121 S Main St, O'Fallon, IL 62269 For Sale

Rare opportunity to acquire an improved one-acre site in downtown Shiloh, Illinois — one of the Metro East’s fastest-growing commercial corridors. Positioned near the signalized intersection of Main and Cross Streets with approximately 10,100 vehicles per day of visibility, the site sits minutes from Memorial Hospital, Siteman Cancer Center, Scott Air Force Base, and Shiloh’s core retail districts, ensuring strong daytime traffic and long-term demand drivers.

Comprised of two parcels zoned Highway Business, the property includes pre-approved commercial building plans through the Village of Shiloh — meaningfully shortening entitlement timelines for a buyer. All major utilities are available on site, and flat topography supports efficient construction for retail, medical, office, restaurant, or service-oriented uses. Ownership will also consider a build-to-suit opportunity.

Strategically positioned near the signalized intersection of Cross Street and Main Street, the site benefits from strong visibility and approximately 10,100 vehicles per day along Main Street. The location places users within minutes of Memorial Hospital, Siteman Cancer Center, Scott Air Force Base, and the surrounding Shiloh retail districts, providing built-in daytime population and continued area growth.