US HWY 76 & 301, Florence, SC 29506

Owner is open to subdividing, build to suit (BTS), partnerships, and ground leases. Feel free to reach out with creative options.

Prime ±4.61-acre development site positioned directly across from Francis Marion University (FMU) in Florence, SC.
Located on Patriot Lane just off E Palmetto Street (US-76), this property sits at the gateway to FMU’s main campus and benefits from strong traffic, a stable student population, and proximity to national retailers including McDonald’s, banking, fuel, and medical services.

The site offers exceptional flexibility for retail, student housing, medical or professional office, or a mixed-use development, subject to zoning and approvals. With immediate access to a signalized intersection at E Palmetto Street, the property provides visibility, connectivity, and convenient ingress/egress within a rapidly developing corridor.

Surrounded by Florence’s major employment drivers—including FMU, McLeod Health, MUSC, QVC, Honda Manufacturing, McCall Farms, and Sonoco—the site sits within one of the region’s most stable and diversified economic ecosystems.

A rare opportunity to control a highly visible, high-impact parcel in a fast-growing university corridor.

Zoning: CMU commercial mixed-use district: The intent of the CMU district is to allow a range of uses including residential, commercial, office, institutional, and light industrial mixed horizontally or vertically on a development site where the predominate use is street-level commercial spaces.

GIS Link: https://www.arcgis.com/apps/webappviewer/index.html?id=fedede8fc1964de2b99aa2de1538ddb9&marker=-79.65741346054757%2C34.19716472421661%2C%2C%2C%2C&markertemplate=%7B%22title%22%3A%22WILKINS%20ROSE%20T%20ETAL%20TRUSTEES%22%2C%22longitude%22%3A-79.65741346054757%2C%22latitude%22%3A34.19716472421661%2C%22isIncludeShareUrl%22%3Atrue%7D&level=19