341 S Plant Ave, Tampa, FL 33606 For Sale

A rare opportunity to acquire two iconic Hyde Park assets prominently positioned at the primary entrance and exit to Davis Islands—one of Tampa’s most affluent and supply-constrained neighborhoods. This highly visible assemblage offers unmatched exposure, architectural presence, and long-term flexibility in the heart of South Tampa.

The offering includes Anderson House at 341 S. Plant Avenue, a three-story ±7,359 SF building, and 334 S. Hyde Park Avenue, a two-story ±3,703 SF building, situated on a combined ±0.94-acre site. Both properties are zoned RO-1, providing highly desirable dual zoning that allows for office and residential uses, a rarity in this submarket and a significant driver of long-term value. City approved 50% parking reduction for zoning requirements.

The property is currently 100% leased to Lecada, an extremely high-end medical aesthetics and wellness practice whose brand, build-out, and clientele align seamlessly with the prestige of Hyde Park and Davis Islands. The tenancy provides stable income today while preserving future optionality for an owner-user, investor, or developer.

Adding to the investment appeal, plans are in place to expand the campus by an additional ±5,468 SF, including a ±4,064 SF three-story office building with ground-floor parking and a two-story ±1,404 SF residential building comprised of two one-bedroom units. This expansion potential offers a clear value-add pathway in a market where new development opportunities are increasingly limited.

With irreplaceable location, dual-use zoning, expansion plans, and credit-worthy tenancy, this Hyde Park assemblage represents a compelling opportunity to acquire a landmark property at the gateway to Davis Islands—one that combines immediate income with long-term strategic upside in one of Tampa’s most coveted corridors.

Total combined acreage = 0.94 acres

Total combined SF = 11,062 SF

Total SF of new development = 5,468 SF

Total SF with new development 16,530 SF