225-227 Union Avenue, Holbrook, NY 11741 For Sale

An exceptional opportunity to acquire a two‑building portfolio situated on a combined 0.79 acres in the heart of Holbrook. This care offering includes a three-bedroom two-bath legal residential rental home and a 6.10 SF professional/medical office building, formerly the well-known Sachem Animal Hospital.

The 12-zoned professional building futures multiple entrances, a flexible layout, oil and gas heat, ample on-site parking, strong visibility, and a partial basement with exterior access. The bulking also includes a freshly painted one-bedroom apartment above, creating an additional income stream or on site operational convenience. The site benefits from tremendous frontage and a double-sided marquee sign, maximizing exposure for any commercial or medical u

The accompanying three bedroom, two-bath home is uniquely positioned with mixed 12 and residential zoning, allowing it to function as a legal residential rental or be repurposed for business use offering exceptional flexibility. The home includes new siding and fresh paint, hardwood and carpet throughout,, new Frigidaire appliances gas heat, a full basement with anterior and exterior entrances, a detached one-car garage with ample storage, and a fully fenced yard, enhancing both usability and tenant appeal

The property's strategic location offers outstanding regional connectivity. It is just minutes from the Station Yards at the Ronkonkoma LIRR and provides easy access to The Long Island Expressway, Sunrise Highway, and other major transportation routes, strengthening both user convenience and long-term investment performance This portfolio represents an incredible opportunity for an end user, investor or operator seeking a versatile, well-positioned asset with significant upside potential