1780 U.S. 49, Florence, MS 39073 For Sale

We are pleased to present an exceptional opportunity to acquire a highly visible, approximately three-acre commercial parcel on Highway 49 in Florence, Mississippi. The site features direct frontage on a recently expanded six-lane highway with traffic counts approaching 40,000 vehicles per day.

Existing improvements include a concrete driveway and paved asphalt area at the front of the site, reducing initial site preparation costs. The remaining acreage offers ample room for expansion and flexible site planning for a variety of commercial uses.

Positioned for maximum exposure and easy access, this site is well-suited for retail, restaurants, service businesses, automotive users, or investment developments seeking strong visibility and convenient ingress and egress. Whether for new construction or expansion, the property delivers the location, scale, and infrastructure to support long-term success.