www.crexi.com - The Commercial Real Estate Exchange
For Lease
All Types 

Sioux Falls, SD Spaces for Lease

482 spaces
Recommended 
Pictures of Retail, Office property located at 7640 S Louise Ave, Sioux Falls, SD 57108 for lease - image #1
$17/SF/YR
RAINTREE CENTER
Retail Space Available • 2,370 SqFt

7640 S Louise Ave Sioux Falls, SD 57108

Pictures of Office property located at 5024 S Bur Oak Pl, Sioux Falls, SD 57108 for lease - image #1
$17/SF/YR
Oakbrook I
Office • 1 space available • 751 SqFt - 4,931 SqFt

5024 S Bur Oak Pl Sioux Falls, SD 57108

Pictures of Retail property located at 1413 N Marion Rd, Sioux Falls, SD 57107 for lease - image #1
$26/SF/YR
Marion Road Retail
Retail • 1 space available • 1,437 SqFt - 4,008 SqFt

1413 N Marion Rd Sioux Falls, SD 57107

Pictures of Industrial property located at 901 E 50th St N, Sioux Falls, SD 57104 for lease - image #1
$8.50/SF/YR
901 E. 50th Street North
Industrial • 1 space available • 8,197 SqFt

901 E 50th St N Sioux Falls, SD 57104

Pictures of Industrial property located at 1000 South Enterprise Avenue, Sioux Falls, SD 57110 for lease - image #1
Undisclosed Rate
Tysdal Storage Building
Cold Storage Building For Lease • 1,400 sqft

1000 South Enterprise Avenue Sioux Falls, SD 57110

Pictures of Office property located at 3800 S Kiwanis Ave, Sioux Falls, SD 57105 for lease - image #1
$16/SF/YR
3800 S Kiwanis Ave
Office • Single tenant • 10,572 SqFt

3800 S Kiwanis Ave Sioux Falls, SD 57105

INTELLIGENCE
Instantly evaluate properties and markets with confidence.
Analyze data, market trends, sales comps, demographics, and more.
Learn More
Pictures of Office property located at 120 S Indiana Ave, Sioux Falls, SD 57103 for lease - image #1
$10.98/SF/YR
120 S Indiana Ave A&B
Office • Single tenant • 1,683 SqFt

120 S Indiana Ave Sioux Falls, SD 57103

Pictures of Retail property located at 5712 E. 18th Street,, Sioux Falls, SD 57110 for lease - image #1
$24 - $28/SF/YR
National Breakfast-Anchored Strip | Dawley Farm Village
National Breakfast-Anchored Strip • 2,080 SqFt - 4,492 SqFt

5712 E. 18th Street, Sioux Falls, SD 57110

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Office, Retail, Industrial property located at 200 S Minnesota Ave, Sioux Falls, SD 57104 for lease - image #1
$18/SF/YR
The Argus Leader Building
Office • 1 space available 10,000 SqFt - 99,070 SqFt

200 S Minnesota Ave Sioux Falls, SD 57104

Pictures of Retail property located at 8505 West 26th Street, Sioux Falls, SD 57106 for lease - image #1
Undisclosed Rate
Westridge Mall
West Side Retail - Ellis Road Corridor

8505 West 26th Street Sioux Falls, SD 57106

Pictures of Land property located at 2409 West Russell Street, Sioux Falls, SD 57104 for lease - image #1
Undisclosed Rate
West Russell Street Retail Site
Retail Strip Center • 0.71 acres

2409 West Russell Street Sioux Falls, SD 57104

Pictures of Retail, Office property located at 427 N Minnesota Ave, Sioux Falls, SD 57104 for lease - image #1
$10 - $11/SF/YR
NorthStar Plaza
Retail • 2 spaces available • 1,168 SqFt - 2,073 SqFt

427 N Minnesota Ave Sioux Falls, SD 57104

Pictures of Office property located at 6805 S Minnesota Ave, Sioux Falls, SD 57108 for lease - image #1
$15/SF/YR
South Minnesota Office
Upper Level Office Space

6805 S Minnesota Ave Sioux Falls, SD 57108

Pictures of Industrial property located at 5512 N 7th Pl, Sioux Falls, SD 57104 for lease - image #1
$9/SF/YR
5512 N 7th Avenue
Industrial • 1 space available • 1,500 SqFt - 3,000 SqFt

5512 N 7th Pl Sioux Falls, SD 57104

Pictures of Retail property located at 2700 S Ellis Rd, Sioux Falls, SD 57106 for lease - image #1
$22 - $24/SF/YR
Westown Marketplace Retail
Retail • 3 spaces available • 1,400 SqFt - 1,899 SqFt

2700 S Ellis Rd Sioux Falls, SD 57106

Pictures of Retail property located at 5001 N Annika Ave, Sioux Falls, SD 57107 for lease - image #1
$23/SF/YR
5001 Retail Center
Retail • 3 spaces available • 1,260 SqFt - 1,728 SqFt

5001 N Annika Ave Sioux Falls, SD 57107

Pictures of Retail property located at 4700 S Sycamore Ave, Sioux Falls, SD 57110 for lease - image #1
$26/SF/YR
Brooks Crossing Retail
Retail • Single tenant • 1,792 SqFt - 9,111 SqFt

4700 S Sycamore Ave Sioux Falls, SD 57110

Pictures of Office property located at 300 S Sycamore Ave, Sioux Falls, SD 57110 for lease - image #1
$11/SF/YR
The 300 Building
Office • Single tenant • 9,578 SqFt

300 S Sycamore Ave Sioux Falls, SD 57110

Pictures of Office property located at 4200 S. Louise Ave, Sioux Falls, SD 57106 for lease - image #1
Undisclosed Rate
Platinum Center
49th & Louise Office Suite • For Lease

4200 S. Louise Ave Sioux Falls, SD 57106

Pictures of Land property located at 7560 S Minnesota Ave, Sioux Falls, SD 57108 for lease - image #1
$22/SF/YR
Dakota Crossing - Lot 4B
Land • Single tenant • 34,823 SqFt

7560 S Minnesota Ave Sioux Falls, SD 57108

Pictures of Industrial property located at 2300 E Rice St, Sioux Falls, SD 57103 for lease - image #1
$5.50/SF/YR
2300 E Rice St, Sioux Falls, SD
151,077 SF Available For Lease

2300 E Rice St Sioux Falls, SD 57103

Pictures of Office property located at 2401 W Trevi Pl, Sioux Falls, SD 57108 for lease - image #1
$22/SF/YR
Three Fountains Office
SW Sioux Falls Office Space

2401 W Trevi Pl Sioux Falls, SD 57108

Pictures of Industrial property located at 1409 N K Ave, Sioux Falls, SD 57104 for lease - image #1
$6.95/SF/YR
Caballo Industrial Lease
Industrial • 2 spaces available • 7,000 SqFt - 8,760 SqFt

1409 N K Ave Sioux Falls, SD 57104

Pictures of Office, Retail property located at 205 E 12th St, Sioux Falls, SD 57104 for lease - image #1
$25/SF/YR
One2
One2 • Downtown Office/Retail • Up to 3,131 USF

205 E 12th St Sioux Falls, SD 57104

Pictures of Office property located at 47168 Haylie St, Sioux Falls, SD 57107 for lease - image #1
$8/SF/YR
47168 Haylie Street
Office • Single tenant • 29,000 SqFt

47168 Haylie St Sioux Falls, SD 57107

Pictures of Retail property located at 3320 S Sycamore Ave, Sioux Falls, SD 57110 for lease - image #1
$18/SF/YR
41st & Sycamore Retail
Retail • 1 space available • 2,280 SqFt

3320 S Sycamore Ave Sioux Falls, SD 57110

Pictures of Industrial property located at 2017 Industrial Street, Tea, SD 57064 for lease - image #1
$11/SF/YR
2017 Industrial Street, East Building
Industrial • 2 spaces available • 5,756 SqFt

2017 Industrial Street Tea, SD 57064

Pictures of Office, Industrial property located at 1829 E 34th St N, Sioux Falls, SD 57104 for lease - image #1
$8.42/SF/YR
1829 E. 34th Street N
5,700 SF Flex Building

1829 E 34th St N Sioux Falls, SD 57104

Pictures of Industrial, Special Purpose property located at 3401 S Centerfield Pl, Sioux Falls, SD 57110 for lease - image #1
$15/SF/YR
Centerfield Place
Industrial • 1 space available • 2,640 SqFt

3401 S Centerfield Pl Sioux Falls, SD 57110

Pictures of Retail, Office property located at 7640 S Louise Ave, Sioux Falls, SD 57108 for lease - image #1
$17/SF/YR
Raintree Center
Professional Office / Retail Space • 1,268 sqft

7640 S Louise Ave Sioux Falls, SD 57108

Pictures of Industrial property located at 47188 Wild Clover Cir, Sioux Falls, SD 57107 for lease - image #1
$13.85/SF/MO
Wild Clover Space
Flex Building for Lease • 2,600 SF

47188 Wild Clover Cir Sioux Falls, SD 57107

Pictures of Retail, Office property located at 2101 W 41st St, Sioux Falls, SD 57105 for lease - image #1
$13 - $13.50/SF/YR
Western Mall
Retail • 3 spaces available • 643 SqFt - 14,145 SqFt

2101 W 41st St Sioux Falls, SD 57105

Pictures of Office property located at 4105 S Carnegie Pl, Sioux Falls, SD 57106 for lease - image #1
Undisclosed Rate
Decoy Office Building
Office • 2 suites available

4105 S Carnegie Pl Sioux Falls, SD 57106

Pictures of Industrial property located at 710 N Ebenezer Ave, Sioux Falls, SD 57107 for lease - image #1
$8.25/SF/YR
Century Business Park
Industrial • 1 space available • 13,628 SF

710 N Ebenezer Ave Sioux Falls, SD 57107

Pictures of Industrial property located at 709 N Kiwanis Ave, Sioux Falls, SD 57104 for lease - image #1
$8.25/SF/YR
Madison Business Center - Suite 709
Industrial • Single tenant • 8,960 SqFt

709 N Kiwanis Ave Sioux Falls, SD 57104

Pictures of Retail property located at 721 W 11th St, Sioux Falls, SD 57104 for lease - image #1
$14.90/SF/YR
West 11th Retail
Convenient Retail Space Near Downtown

721 W 11th St Sioux Falls, SD 57104

Pictures of Office property located at 4900 N Velocity Ave, Sioux Falls, SD 57104 for lease - image #1
$8.50/SF/YR
Velocity Office
Office and Lab in Northeast Sioux Falls

4900 N Velocity Ave Sioux Falls, SD 57104

Pictures of Office property located at 5929 S Mogen Ave, Sioux Falls, SD 57108 for lease - image #1
$5 - $14/SF/YR
5929 S Mogen Avenue
Office • 2 spaces available • 3,530 SqFt - 14,400 SqFt

5929 S Mogen Ave Sioux Falls, SD 57108

Pictures of Retail property located at 151 E 4th Pl, Sioux Falls, SD 57104 for lease - image #1
$25/SF/YR
Steel District Retail
Retail • 5 spaces available • 1,002 SqFt - 5,790 SqFt

151 E 4th Pl Sioux Falls, SD 57104

Pictures of Office property located at 5032 S Bur Oak Pl, Sioux Falls, SD 57108 for lease - image #1
$17.50/SF/YR
Oakbrook II
Office • 1 space available • 1,818 SqFt

5032 S Bur Oak Pl Sioux Falls, SD 57108

Pictures of Office property located at 6330 S Western Ave, Sioux Falls, SD 57108 for lease - image #1
$18.50/SF/YR
HEATHER RIDGE OFFICE PARK
Professional Office Park Space For Lease

6330 S Western Ave Sioux Falls, SD 57108

Pictures of Retail property located at 1400 W 12th St, Sioux Falls, SD 57104 for lease - image #1
Undisclosed Rate
1400 W 12th Street
Retail • Single tenant • 540 SqFt

1400 W 12th St Sioux Falls, SD 57104

Pictures of Retail property located at 5020 S Highline Ave, Sioux Falls, SD 57110 for lease - image #1
$26 - $28/SF/YR
Harvest Creek Strip Mall
Retail • 3 spaces available • 1,649 sq. ft. - 5,112 sq. ft.

5020 S Highline Ave Sioux Falls, SD 57110

Pictures of Retail property located at 1506 E 69th St, Sioux Falls, SD 57108 for lease - image #1
$21/SF/YR
Stadium Crossing I
Retail • 1 space available • 1,010 SqFt

1506 E 69th St Sioux Falls, SD 57108

Pictures of Retail property located at 2103 S Minnesota Ave, Sioux Falls, SD 57105 for lease - image #1
$10/SF/YR
Southway Center
Retail Space • Minnesota Avenue

2103 S Minnesota Ave Sioux Falls, SD 57105

Pictures of Industrial property located at 5500 Wireless St, Sioux Falls, SD 57107 for lease - image #1
$7.75/SF/YR
The Docks
Industrial • 1 space available • 50,000 SqFt - 122,290 SqFt

5500 Wireless St Sioux Falls, SD 57107

Pictures of Industrial property located at N Bahnson Ave, Sioux Falls, SD 57104 for lease - image #1
$8.50/SF/YR
Sweetman Spec Building
Industrial • 2 spaces available • 50,400 SqFt

N Bahnson Ave Sioux Falls, SD 57104

Pictures of Office property located at 1800 S Summit Ave, Sioux Falls, SD 57105 for lease - image #1
$12.50/SF/YR
26th Street Office
Office • 3 spaces available • 2,190 SqFt - 6,570 SqFt

1800 S Summit Ave Sioux Falls, SD 57105

Pictures of Retail property located at 410 W 26th St, Sioux Falls, SD 57105 for lease - image #1
$16/SF/YR
Minnesota Avenue Salon Lease
Retail • 1 space available • 2,800 SqFt

410 W 26th St Sioux Falls, SD 57105

Pictures of Office, Industrial property located at 3200 W Sencore Dr, Sioux Falls, SD 57107 for lease - image #1
Undisclosed Rate
Valentus
Office/Warehouse/Industrial

3200 W Sencore Dr Sioux Falls, SD 57107

Pictures of Industrial property located at 6408 W 12th St, Sioux Falls, SD 57107 for lease - image #1
Undisclosed Rate
12th Street Industrial Spaces
Industrial • 1 space available • 4,500 SqFt - 11,087 SqFt

6408 W 12th St Sioux Falls, SD 57107

Pictures of Office property located at 6340 S Western Ave, Sioux Falls, SD 57108 for lease - image #1
$20/SF/YR
HEATHER RIDGE OFFICE PARK
Professional Office Park Space Available

6340 S Western Ave Sioux Falls, SD 57108

Pictures of Retail, Office property located at 4407 E 57th St, Sioux Falls, SD 57108 for lease - image #1
$24 - $27/SF/YR
Graystone Plaza
Graystone Plaza for Lease

4407 E 57th St Sioux Falls, SD 57108

Pictures of Office property located at 409 E 41st St, Sioux Falls, SD 57105 for lease - image #1
Undisclosed Rate
409 E 41st St
Office • 1 space available • 288 SqFt

409 E 41st St Sioux Falls, SD 57105

Pictures of Office property located at 5019 S Bur Oak Pl, Sioux Falls, SD 57108 for lease - image #1
$19/SF/YR
5019 S Bur Oak Place
Office • Single tenant • 2,172 SqFt

5019 S Bur Oak Pl Sioux Falls, SD 57108

Pictures of Retail, Office property located at 6701 W 41st St, Sioux Falls, SD 57106 for lease - image #1
$15/SF/YR
Sertoma Plaza
Retail • 1 space available • 2,340 SqFt

6701 W 41st St Sioux Falls, SD 57106

Pictures of Retail property located at 1216 E 57th St, Sioux Falls, SD 57108 for lease - image #1
$18/SF/YR
Oak Ridge Plaza
Retail • 2 spaces available • 1,000 SqFt - 2,237 SqFt

1216 E 57th St Sioux Falls, SD 57108

Pictures of Office property located at 1800 W 12th St, Sioux Falls, SD 57104 for lease - image #1
$9.75/SF/YR
West 12th Office
Office • Single tenant • 11,285 SqFt

1800 W 12th St Sioux Falls, SD 57104

Pictures of Office property located at 101 Sout Reid Stret, Suite 307, Sioux Falls, SD 5103 for lease - image #1
$84 - $1,775/SF/YR
Regus CNA Building
Message or Call us to book a tour & get more information!

101 Sout Reid Stret, Suite 307 Sioux Falls, SD 5103

Pictures of Retail property located at 720 S. Sycamore Ave, Sioux Falls, SD 57110 for lease - image #1
$31.09/SF/YR
Becker Mall
Retail • Single tenant

720 S. Sycamore Ave Sioux Falls, SD 57110

Nearby Spaces

Show Less

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591