South Carolina Office Space For Rent | Commercial Leasing | Crexi.com

www.crexi.com - The Commercial Real Estate Exchange

Show Map

Results

Insights

2,661 spaces

Pictures of Retail, Office property located at 2270 Celanese Rd, Rock Hill, SC 29732 for lease - image #1

$33/SF/YR

2270 Celanese Rd

Retail • 1 space available • 2,500 SqFt - 9,975 SqFt

2270 Celanese Rd Rock Hill, SC 29732

Pictures of Industrial, Office property located at 552 Mayfield Road, Duncan, SC 29334 for lease - image #1

Undisclosed Rate

Merovan at Duncan

Industrial • 3 spaces available • 6,250 SqFt - 12,500 SqFt

552 Mayfield Road Duncan, SC 29334

Pictures of Office, Industrial property located at 377 Rubin Center Drive, Fort Mill, SC 29708 for lease - image #1

$15 - $18/SF/YR

Stateline Business Park

Office • 5 spaces available • 1,303 SqFt - 6,399 SqFt

377 Rubin Center Drive Fort Mill, SC 29708

Pictures of Office, Retail property located at 3800 Houndsfield Avenue, Myrtle Beach, SC 29577 for lease - image #1

$27 - $29/SF/YR

Oleander Executive Center

Office • 11 spaces available • 1,173 SqFt - 3,958 SqFt

3800 Houndsfield Avenue Myrtle Beach, SC 29577

Pictures of Office, Land property located at 35 Brookfield Oaks Dr, Greenville, SC 29607 for lease - image #1

Undisclosed Rate

35 Brookfield Oaks Drive

Office • Single tenant • 1 acre

35 Brookfield Oaks Dr Greenville, SC 29607

Pictures of Office property located at 101 Greystone Blvd, Columbia, SC 29210 for lease - image #1

$17/SF/YR

101 Greystone Blvd

Office • 1 space available • 242,444 SqFt

101 Greystone Blvd Columbia, SC 29210

INTELLIGENCE

Instantly evaluate properties and markets with confidence.

Analyze data, market trends, sales comps, demographics, and more.

Pictures of Office property located at 236 Union Street, Spartanburg, SC 29302 for lease - image #1

$10/SF/MO

236 Union Street

±23,331 SF OFFICE/FLEX SPACE AVAILABLE FOR LEASE

236 Union Street Spartanburg, SC 29302

Pictures of Office property located at 556 Perry Ave, Greenville, SC 29611 for lease - image #1

$28.50/SF/YR

Poe West

Office • 1 space available • 3,633 SqFt

556 Perry Ave Greenville, SC 29611

See New Listings First!

Save your filters and get alerts when new properties hit the market.

Pictures of Retail, Office property located at 1241 Pendleton Street, Greenville, SC 29611 for lease - image #1

$28/SF/YR

1241 Pendleton St

Retail • 1 space available • 2,280 SqFt

1241 Pendleton Street Greenville, SC 29611

Pictures of Office property located at 10 Memorial Medical Drive, Greenville, SC 29605 for lease - image #1

$13/SF/YR

10 Memorial Medical Drive

Office • Single tenant • 7,000 SqFt

10 Memorial Medical Drive Greenville, SC 29605

Pictures of Retail, Office property located at 1171 Market St, Fort Mill, SC 29708 for lease - image #1

$25 - $32/SF/YR

1171 Market Street, Baxter Village Office Suite 101

Retail • Single tenant • 1,081 SqFt

1171 Market St Fort Mill, SC 29708

Pictures of Office, Industrial property located at 39 Main St, Jackson, SC 29831 for lease - image #1

$11/SF/YR

6,000 sq. ft. Office / Warehouse

New Construction Office/Warehouse

39 Main St Jackson, SC 29831

Pictures of Industrial, Office property located at 1301 Charleston Regional Pkwy, Charleston, SC 29492 for lease - image #1

virtual tour

Undisclosed Rate

Cubework Charleston

Industrial • 2 spaces available • 300 SqFt - 50,000 SqFt

1301 Charleston Regional Pkwy Charleston, SC 29492

Pictures of Office property located at 11945 Grandhaven Dr, Murrells Inlet, SC 29576 for lease - image #1

$25/SF/YR

Grandhaven Center

Office • 1 space available • 900 SqFt

11945 Grandhaven Dr Murrells Inlet, SC 29576

Pictures of Office property located at 1800 Husted Rd, Conway, SC 29526 for lease - image #1

$16/SF/YR

1800 Husted Rd

Office • 1 space available • 3,718 SqFt

1800 Husted Rd Conway, SC 29526

Pictures of Retail, Office property located at 1642 SC-160, Fort Mill, SC 29708 for lease - image #1

Undisclosed Rate

Carolina Commerce Center

Retail • 2 spaces available • 980 SqFt - 1,982 SqFt

1642 SC-160 Fort Mill, SC 29708

Pictures of Retail, Office property located at 818 MAIN ST, LITTLE MOUNTAIN, SC 29075 for lease - image #1

$18.50/SF/YR

818 MAIN ST LITTLE MOUNTAIN SC 29075

Main Street Retail and Office on HWY 76 Little Mountain

818 MAIN ST LITTLE MOUNTAIN, SC 29075

Pictures of Office property located at 211 King Street, Charleston, SC 29401 for lease - image #1

$35/SF/YR

211 King Street

Sub-Lease/2,638 SQ FT - 8 Private Offices

211 King Street Charleston, SC 29401

Pictures of Retail, Office, Industrial property located at 110 Joel Street, Lake City, SC 29560 for lease - image #1

$2,000/SF/MO

110 Joel Street

2,500 SF Commercial Building for Lease – Prime Lake City Location – $2,000/Month NNN

110 Joel Street Lake City, SC 29560

Pictures of Office property located at 65 Fairchild St, Charleston, SC 29492 for lease - image #1

video

Undisclosed Rate

65 Fairchild St

Office • 6,948 SqFt - 25,570 SqFt

65 Fairchild St Charleston, SC 29492

Pictures of Office property located at 518 Meritage Street, Greer, SC 29651 for lease - image #1

$28/SF/YR

518 Meritage Street

Office

518 Meritage Street Greer, SC 29651

Pictures of Office, Special Purpose property located at 518 Meritage Street, Greer, SC 29651 for lease - image #1

Undisclosed Rate

518 Meritage Street

518 Meritage Street Greer, SC 29651

Pictures of Office property located at 40 Calhoun Street Suite 305 #Suite 305-South, Charleston, SC 29401 for lease - image #1

$38/SF/YR

Charleston Gateway Center

Office • Single tenant • 1,356 SqFt

40 Calhoun Street Suite 305 #Suite 305-South Charleston, SC 29401

Pictures of Office property located at 40 Calhoun Street Suite 205 #Suite 205-South, Charleston, SC 29401 for lease - image #1

$38/SF/YR

Charleston Gateway Center

Charleston Gateway Office Space for lease

40 Calhoun Street Suite 205 #Suite 205-South Charleston, SC 29401

Pictures of Office property located at 4105 Faber Place Drive, North Charleston, SC 29405 for lease - image #1

$32/SF/YR

4105 Faber Pl Drive # 410

Office • 1 space available • 3,442 SqFt

4105 Faber Place Drive North Charleston, SC 29405

Pictures of Office property located at 297 Seven Farms Drive Ste 203, Charleston, SC 29492 for lease - image #1

$38/SF/YR

297 Seven Farms Drive Ste 203

Office • Single tenant • 2,118 SqFt

297 Seven Farms Drive Ste 203 Charleston, SC 29492

Pictures of Retail, Office, Special Purpose property located at 4465 Tile Dr, North Charleston, SC 29405 for lease - image #1

$24 - $27/SF/YR

4465 Tile Drive | Flex Office for Lease

Retail • 1 space available • 500 SqFt - 3,000 SqFt

4465 Tile Dr North Charleston, SC 29405

Pictures of Office property located at 6296 Rivers Avenue Suite 305, Charleston, SC 29406 for lease - image #1

$22/SF/YR

Trident United Way Building

Office • Single tenant • 1,638 SqFt

6296 Rivers Avenue Suite 305 Charleston, SC 29406

Pictures of Industrial, Retail, Office property located at 121 Hemphill Ct, Summerville, SC 29483 for lease - image #1

$12 - $14/SF/YR

121-141 Hemphill Ct

Industrial • 2 spaces available • 870 SqFt - 2,550 SqFt

121 Hemphill Ct Summerville, SC 29483

Pictures of Office, Special Purpose property located at 216 W 7th North Street, Summerville, SC 29483 for lease - image #1

$22.05/SF/YR

216 W 7th North Street

Special Purpose Office Space • Summerville

216 W 7th North Street Summerville, SC 29483

Pictures of Retail, Office property located at 3316 Ashley Phosphate Road, North Charleston, SC 29418 for lease - image #1

$17.72/SF/YR

3316 Ashley Phosphate Road #12

Retail/Office space for SubLease

3316 Ashley Phosphate Road North Charleston, SC 29418

Pictures of Industrial, Retail, Office property located at 313 N Maple Street, Summerville, SC 29483 for lease - image #1

$21/SF/YR

313 N Maple Street

Industrial • Single tenant • 1,875 SqFt - 2,220 SqFt

313 N Maple Street Summerville, SC 29483

Pictures of Office property located at 40 Calhoun Street # 230, Charleston, SC 29401 for lease - image #1

$40 - $42/SF/YR

40 Calhoun Street # 230

Office • Single tenant • 1,410 SqFt

40 Calhoun Street # 230 Charleston, SC 29401

Pictures of Office, Retail property located at 1247 Nexton Parkway, Summerville, SC 29486 for lease - image #1

$40/SF/YR

1247 Nexton Parkway Suite 104

Office • 1 space available • 1,492 SqFt

1247 Nexton Parkway Summerville, SC 29486

Pictures of Office property located at 4285 Spruill Avenue, North Charleston, SC 29405 for lease - image #1

$42/SF/YR

4285 Spruill Avenue Suite 200

Office • 1 space available • 3,000 SqFt

4285 Spruill Avenue North Charleston, SC 29405

Pictures of Office property located at 134 Meeting Street # 300, Charleston, SC 29401 for lease - image #1

$45/SF/YR

134 Meeting Street # 300

Office • Single tenant • 15,255 SqFt

134 Meeting Street # 300 Charleston, SC 29401

Pictures of Office property located at 229 Huger Street, Charleston, SC 29403 for lease - image #1

$41/SF/YR

229 Huger Street

Office • Single tenant • 3,767 SqFt

229 Huger Street Charleston, SC 29403

Pictures of Office property located at 255 E Bay St, Charleston, SC 29401 for lease - image #1

$35/SF/YR

255 East Bay Street

Office • Single tenant • 4,730 SqFt

255 E Bay St Charleston, SC 29401

Pictures of Office property located at 1535 Hobby St, North Charleston, SC 29405 for lease - image #1

$27.50 - $28.50/SF/YR

1535 Hobby Street

Office • 1 space available • 1,200 SqFt - 11,300 SqFt

1535 Hobby St North Charleston, SC 29405

Pictures of Office, Restaurant property located at 463 King St, Charleston, SC 29403 for lease - image #1

$34/SF/YR

463 King Street

Office • 1 space available • 3,204 SqFt

463 King St Charleston, SC 29403

Pictures of Retail, Office, Restaurant property located at 1237 Nexton Pkwy, Summerville, SC 29486 for lease - image #1

$45/SF/YR

The Hub @ Nexton Building 2

Retail • 1 space available • 3,595 SqFt

1237 Nexton Pkwy Summerville, SC 29486

Pictures of Retail, Office, Land property located at Sigma Drive, Summerville, SC 29486 for lease - image #1

Undisclosed Rate

±1.0 Ac at Nexton

Retail • Single tenant • 1 acre

Sigma Drive Summerville, SC 29486

Pictures of Office property located at 2070 Northbrook Blvd., North Charleston, SC 29406 for lease - image #1

$19.95/SF/YR

2070 Northbrook Blvd.

Office • 1 space available • 1,000 SqFt - 2,200 SqFt

2070 Northbrook Blvd. North Charleston, SC 29406

Pictures of Office property located at 125 Fairchild Street, Charleston, SC 29492 for lease - image #1

$26 - $28/SF/YR

125 Fairchild Street

Office • 1 space available • 6,500 SqFt - 52,000 SqFt

125 Fairchild Street Charleston, SC 29492

Pictures of Office property located at 814 US-17, Mount Pleasant, SC 29464 for lease - image #1

$34/SF/YR

New, First-Gen Office Space in Mt. Pleasant 29464

Office • Single tenant • 2,756 SqFt

814 US-17 Mount Pleasant, SC 29464

Carroll Realty, Inc

Pictures of Industrial, Office, Retail property located at Parkway Entire Site, Moncks Corner, SC 29461 for lease - image #1

$6.50/SF/YR

West Branch Commerce Park

Industrial • Single tenant • 50,000 SqFt - 1,500,000 SqFt

Parkway Entire Site Moncks Corner, SC 29461

Jones Lang LaSalle Brokerage

Pictures of Office property located at 1501 Belle Isle Avenue, Mt Pleasant, SC 29464 for lease - image #1

$1/SF/YR

1501 Belle Isle, Suite 200

1501 Belle Isle Avenue, Suite 200 • Mount Pleasant, SC - Available for Sublease • 6,008 SF

1501 Belle Isle Avenue Mt Pleasant, SC 29464

Pictures of Office property located at 65 FAIRCHILD ST, CHARLESTON, SC 29492 for lease - image #1

$41/SF/MO

65 FAIRCHILD ST CHARLESTON SC 29492

65 FAIRCHILD ST CHARLESTON, SC 29492

Pictures of Retail, Office, Restaurant property located at 838 Morrison Dr, Charleston, SC 29403 for lease - image #1

$46/SF/YR

Morrison Yard

Retail • 3 spaces available • 1,360 SqFt - 6,786 SqFt

838 Morrison Dr Charleston, SC 29403

Pictures of Office, Industrial property located at 4509 Savannah Hwy, Ravenel, SC 29470 for lease - image #1

$15/SF/YR

South Stono Business Park

Office • 2 spaces available • 4,533 SqFt

4509 Savannah Hwy Ravenel, SC 29470

Pictures of Industrial, Office property located at 3567 Meeting Street Road, North Charleston, SC 29405 for lease - image #1

$16.50 - $18.50/SF/YR

3567 Meeting Street Road

Industrial • 2 spaces available • 925 SqFt - 26,489 SqFt

3567 Meeting Street Road North Charleston, SC 29405

Pictures of Office property located at 1200 Innovation Way # 200, Mount Pleasant, SC 29466 for lease - image #1

$28/SF/YR

1200 Innovation Way # 200

Office • Single tenant • 5,000 SqFt - 14,084 SqFt

1200 Innovation Way # 200 Mount Pleasant, SC 29466

Pictures of Office, Industrial property located at 4995 Lacross Road Suite 1300, North Charleston, SC 29406 for lease - image #1

$22/SF/YR

Rivergate I

Office • Single tenant • 6,158 SqFt

4995 Lacross Road Suite 1300 North Charleston, SC 29406

Pictures of Office, Industrial property located at 1941 Savage Road Suite D #Suite 500-D, Charleston, SC 29407 for lease - image #1

$19/SF/YR

1941 Savage Road Suite D #Suite 500-D

Office • Single tenant • 2,080 SqFt

1941 Savage Road Suite D #Suite 500-D Charleston, SC 29407

Pictures of Office property located at 4975 Lacross Road Suite 303, North Charleston, SC 29406 for lease - image #1

$25/SF/YR

Rivergate II

Office • Single tenant • 641 SqFt - 1,518 SqFt

4975 Lacross Road Suite 303 North Charleston, SC 29406

Pictures of Office property located at 1180 Sam Rittenberg Boulevard # 215, Charleston, SC 29407 for lease - image #1

$20/SF/YR

1180 Sam Rittenberg Boulevard # 215

Office • Single tenant • 1,872 SqFt

1180 Sam Rittenberg Boulevard # 215 Charleston, SC 29407

Pictures of Office property located at 525 E Bay Street # 203, Charleston, SC 29403 for lease - image #1

$39/SF/YR

525 E Bay Street # 203

Office • Single tenant • 1,901 SqFt

525 E Bay Street # 203 Charleston, SC 29403

Pictures of Office property located at 525 E Bay Street # 100, Charleston, SC 29403 for lease - image #1

$42 - $44/SF/YR

525 E Bay Street # 100

Office • Single tenant • 5,000 SqFt - 14,515 SqFt

525 E Bay Street # 100 Charleston, SC 29403

Pictures of Office, Retail, Restaurant property located at 1237 Nexton Parkway, Summerville, SC 29486 for lease - image #1

virtual tour

$45/SF/YR

The Hub @ Nexton

Office • 1 space available • 3,595 SqFt - 30,000 SqFt

1237 Nexton Parkway Summerville, SC 29486

Pictures of Office property located at 180 E Bay Street, Charleston, SC 29401 for lease - image #1

$38/SF/YR

180 E Bay Street

Office • 1 space available • 76 SqFt - 4,000 SqFt

180 E Bay Street Charleston, SC 29401

Results per page:

Previous 1 .. 6 7 8 .. 9 10 11 12 .. 25 Next

Nearby Office Spaces

Show Less

Show Less

For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]

5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC

© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591

Do not sell or share my personal information

Tax Notices Licensing Terms of Service Privacy Policy Site Map