www.crexi.com - The Commercial Real Estate Exchange
For Sale
Office 

South Carolina Office Properties for Sale

751 results
Pictures of Office, Retail property located at 132 Chesterfield Street South, Aiken, SC 29801 for sales - image #1
$749,900
132 Chesterfield Street South
Office • 2,163 SqFt

132 Chesterfield Street South Aiken, SC 29801

Pictures of Office property located at 3551 Moore Duncan Hwy, Moore, SC 29369 for sales - image #1
$410,000
Office Building on Moore Duncan Hwy
Office • 3,263 SqFt

3551 Moore Duncan Hwy Moore, SC 29369

Pictures of Mixed Use, Office, Multifamily, Retail property located at 209 E 3rd North Street, Summerville, SC 29483 for sales - image #1
Opportunity Zone
$450,000
209 E 3rd North Street
Mixed Use • 881 SqFt

209 E 3rd North Street Summerville, SC 29483

Pictures of Land, Mixed Use, Office, Special Purpose property located at 1510 Canal Dr, Columbia, SC 29210 for sales - image #1
$399,000
1510 Canal Dr, Columbia, SC 29210
Investment Opportunity

1510 Canal Dr Columbia, SC 29210

Pictures of Retail, Office property located at 401 N Congress St, Winnsboro, SC 29180 for sales - image #1
$250,000
401 N. Congress St
Standalone retail/office building with plenty of parking.

401 N Congress St Winnsboro, SC 29180

Pictures of Industrial, Office property located at 742 W Carolina Ave, Hartsville, SC 29550 for sales - image #1
$450,000
742 & 744 W Carolina Ave
±6,120 SF space offering excellent visibility near Downtown Hartsville.

742 W Carolina Ave Hartsville, SC 29550

Pictures of Office property located at 302 N White St, Lancaster, SC 29720 for sales - image #1
Opportunity Zone
$325,000
Prime commercial opportunity in the heart of Lancaster!
Commercial building offering an ideal setup for a single or multiple businesses.

302 N White St Lancaster, SC 29720

Pictures of Office, Land property located at 1242 White Flat Rd, Mount Pleasant, SC 29464 for sales - image #1
$799,000
Mt. Pleasant Office Building & Land - For Sale - New Price!
Office Building & Land Available - South Mt. Pleasant - New Price!

1242 White Flat Rd Mount Pleasant, SC 29464

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Office property located at 7193 St Andrews Rd, Columbia, SC 29212 for sales - image #1
$699,000
St Andrews Executive Offices
Office • 3,500 SqFt

7193 St Andrews Rd Columbia, SC 29212

Pictures of Office property located at 9 Halton Green Way, Greenville, SC 29607 for sales - image #1
$2,500,000
9 Halton Green Way
Office • 6,136 SqFt

9 Halton Green Way Greenville, SC 29607

Pictures of Office property located at 174 E Bay St, Charleston, SC 29401 for sales - image #1
$1,900,000
174 East Bay Street
Office • 4,096 SqFt

174 E Bay St Charleston, SC 29401

Pictures of Office, Mixed Use, Industrial property located at 1525 Ashley River Road, Charleston, SC 29407 for sales - image #1
$3,750,000
1525 Ashley River Road
Office • 8,640 SqFt

1525 Ashley River Road Charleston, SC 29407

Pictures of Mixed Use, Office, Retail property located at 3802 State Rd S-8-52, Saint Stephen, SC 29479 for sales - image #1
$369,000
Opportunity Zone | Building & Acerage | Visible Highway
Mixed Use • 768 SqFt Building • 6.98 Acres

3802 State Rd S-8-52 Saint Stephen, SC 29479

Pictures of Office, Retail property located at 104 Court Square, Abbeville, SC 29620 for sales - image #1
$175,000
104 Court Square
Office • 3,200 SqFt

104 Court Square Abbeville, SC 29620

Pictures of Industrial, Office property located at 3860 Faber Pl Drive, North Charleston, SC 29405 for sales - image #1
$15,750,000
3860 Faber Pl Drive
Industrial • 82,228 SqFt

3860 Faber Pl Drive North Charleston, SC 29405

Pictures of Office property located at 1845 Savage Road, Charleston, SC 29407 for sales - image #1
$1,300,000
1845 Savage Rd
Office • 3,383 SqFt

1845 Savage Road Charleston, SC 29407

Pictures of Office property located at 811 Sunset Boulevard, West Columbia, SC 29169 for sales - image #1
Opportunity Zone
$1,280,000
811 Sunset Boulevard
Office • 4,343 SF

811 Sunset Boulevard West Columbia, SC 29169

Pictures of Office property located at 260 West Coleman Boulevard, Unit B, Mount Pleasant, SC 29464 for sales - image #1
$1,740,500
260 West Coleman Boulevard, Unit B
Office • 4,365 SqFt

260 West Coleman Boulevard, Unit B Mount Pleasant, SC 29464

Pictures of Office, Industrial property located at 264 Neely Ferry Road, Simpsonville, SC 29680 for sales - image #1
$1,700,000
264 Neely Ferry Road
Flex Building For Sale or Lease

264 Neely Ferry Road Simpsonville, SC 29680

Pictures of Retail, Business for Sale, Industrial, Multifamily, Mixed Use, Land, Office property located at 1651 Main Street, Bonneau, SC 29431 for sales - image #1
$15,000,000
1651 Main Street
Retail • 3,150 SqFt

1651 Main Street Bonneau, SC 29431

Pictures of Office property located at 307 N Main St, Marion, SC 29571 for sales - image #1
Opportunity Zone
Unpriced
307 N Main St
Office • 12,919 SqFt

307 N Main St Marion, SC 29571

Pictures of Business for Sale, Office property located at 367 Wando Place Drive, Mount Pleasant, SC 29464 for sales - image #1
$3,600,000
367 Wando Place Drive
Business for Sale • 7,000 SqFt

367 Wando Place Drive Mount Pleasant, SC 29464

Pictures of Mixed Use, Office property located at 318 N Magnolia Street, Summerville, SC 29483 for sales - image #1
Opportunity Zone
$1,150,000
318 N Magnolia Street
Mixed Use • 2,442 SF

318 N Magnolia Street Summerville, SC 29483

Pictures of Mixed Use, Land, Retail, Office property located at Harrison Bridge Road at Merrydale Farms Drive, Simpsonville, SC 29680 for sales - image #1
$4,750,000
Harrison Bridge Road at Merrydale Farms Drive
Mixed Use

Harrison Bridge Road at Merrydale Farms Drive Simpsonville, SC 29680

Pictures of Office property located at 198 Rutledge Avenue Ste 1, Charleston, SC 29403 for sales - image #1
$1,740,000
198 Rutledge Avenue Ste 1
Built out Medical Offices with off street parking in the heart of downtown charleston.

198 Rutledge Avenue Ste 1 Charleston, SC 29403

Pictures of Office property located at 1516 Old Trolley Road, Summerville, SC 29485 for sales - image #1
$4,100,000
1516 Old Trolley Road
Office • 16,186 SqFt

1516 Old Trolley Road Summerville, SC 29485

Pictures of Office property located at 120 Broadus Ave, Greenville, SC 29601 for sales - image #1
$7,000,000
120 Broadus Ave.
Investment Opportunity Downtown Greenville • 20,000 SF

120 Broadus Ave Greenville, SC 29601

Pictures of Office property located at 174 East Bay Street, Charleston, SC 29401 for sales - image #1
$1,900,000
174 East Bay Street, C
High Profile Downtown Office on East Bay Parking Available

174 East Bay Street Charleston, SC 29401

Pictures of Retail, Multifamily, Office property located at 916 Bay Street, Beaufort, SC 29902 for sales - image #1
$5,250,000
916 Bay Street
More than a building, it's a chance to reimagine a cornerstone of Beaufort's historic district.

916 Bay Street Beaufort, SC 29902

Pictures of Office property located at 170 Meeting Street, Charleston, SC 29401 for sales - image #1
$14,400,000
170 Meeting Street
Office • 34,400 SqFt

170 Meeting Street Charleston, SC 29401

Pictures of Business for Sale, Industrial, Retail, Mixed Use, Office property located at 105 Lamplight Circle, Summerville, SC 29483 for sales - image #1
$1,195,000
105 Lamplight Circle
Business for Sale • 4,000 SqFt

105 Lamplight Circle Summerville, SC 29483

Pictures of Office property located at 50 St Mark Rd, Taylors, SC 29687 for sales - image #1
$319,000
Taylors Office for Sale
Lower Level Leased through Fall of 2026

50 St Mark Rd Taylors, SC 29687

Pictures of Office property located at 907 Bell St., Conway, SC 29526 for sales - image #1
Opportunity Zone
$324,900
Horry
Office • 2,474 SqFt

907 Bell St. Conway, SC 29526

Pictures of Office property located at 327 Main Street, Greenwood, SC 29646 for sales - image #1
$195,000
327 Main Street - 6th or 8th Floor
Amazing Space in the Heart of Downtown Greenwood!

327 Main Street Greenwood, SC 29646

Pictures of Office property located at 1119 Pick Pocket Plantation Drive, Beaufort, SC 29902 for sales - image #1
$6,000,000
Possible Conversion to Behavioral with Special Use Permit

1119 Pick Pocket Plantation Drive Beaufort, SC 29902

Pictures of Industrial, Land, Mixed Use, Office, Self Storage property located at 4819 SC-101, Woodruff, SC 29388 for sales - image #1
video
$2,300,000
4819 Highway 101
Fastest growing area in the STATE!

4819 SC-101 Woodruff, SC 29388

Pictures of Office property located at 2 Hatcher Creek Street, Simpsonville, SC 29680 for sales - image #1
$2,100,000
2 Hatcher Creek Street
Available for sale or lease

2 Hatcher Creek Street Simpsonville, SC 29680

Pictures of Office, Industrial, Land property located at 4234 Hwy 9 W, Wallace, SC 29596 for sales - image #1
Opportunity Zone
$350,000
Value add near signalized intersection
Near Hwy 9 / Hwy 1 intersection

4234 Hwy 9 W Wallace, SC 29596

Pictures of Office, Mixed Use, Special Purpose property located at 137 Cedar Drive, Saint Stephen, SC 29479 for sales - image #1
Opportunity Zone
$300,000
137 Cedar Drive
Well-maintained Medical Office for Sale

137 Cedar Drive Saint Stephen, SC 29479

Pictures of Retail, Office property located at 2021 State Street, Cayce, SC 29033 for sales - image #1
Opportunity Zone
Unpriced
2021 State Street
Retail • 1,450 SqFt

2021 State Street Cayce, SC 29033

Pictures of Industrial, Office, Mixed Use, Retail property located at 137 Cedar Drive, Saint Stephen, SC 29479 for sales - image #1
Opportunity Zone
$250,000
137 Cedar Drive
Industrial • 2,074 SqFt

137 Cedar Drive Saint Stephen, SC 29479

Pictures of Office property located at 21 Gamecock Avenue # D, Charleston, SC 29407 for sales - image #1
$695,000
21 Gamecock Avenue # D
Office • 2,184 SqFt

21 Gamecock Avenue # D Charleston, SC 29407

Pictures of Office, Mixed Use property located at 203 Eddie Chasteen Drive, Walterboro, SC 29488 for sales - image #1
$494,000
203 Eddie Chasteen Drive
Office • 6.00% CAP • 5,054 SqFt

203 Eddie Chasteen Drive Walterboro, SC 29488

Pictures of Office property located at 1609 Constitution Boulevard, Rock Hill, SC 29732, 1029 West Meeting Street, Lancaster, SC 29720, 902 West Meeting Street, Lancaster, SC 29720 for sales - image #1
Opportunity Zone
Unpriced
1609 Constitution Boulevard
Strategic Medical Real Estate Investment Anchored by Established Cardiology Practice

3 LOCATIONS

Pictures of Office property located at 7 Technology Circle, Columbia, SC 29203 for sales - image #1
$6,250,000
7 Technology Circle
Office • 87,249 SqFt

7 Technology Circle Columbia, SC 29203

Pictures of Mixed Use, Retail, Land, Office property located at 2090 Peach Orchard Road, Sumter, SC 29154 for sales - image #1
$750,000
2090 Peach Orchard Road
Mixed Use • 10,423 SqFt

2090 Peach Orchard Road Sumter, SC 29154

Pictures of Office property located at 900 Island Park Dr, Charleston, SC 29492 for sales - image #1
Unpriced
900 Island Park Drive
Office • 38,000 SqFt

900 Island Park Dr Charleston, SC 29492

Pictures of Mixed Use, Office, Land, Multifamily, Retail property located at 1224 Wappoo Road, Charleston, SC 29407 for sales - image #1
$1,850,000
1224 Wappoo Road
Retail/Office/Multi-Family Investment Opportunity

1224 Wappoo Road Charleston, SC 29407

Pictures of Retail, Office, Special Purpose property located at 101 Misty Drive, West Union, SC 29696 for sales - image #1
$350,000
101 Misty Drive
High-Visibility Commercial Property on Highway 28 offering excellent exposure

101 Misty Drive West Union, SC 29696

Pictures of Office property located at 852 Gold Hill Road, Fort Mill, SC 29708 for sales - image #1
$649,900
Gold Hill Commerce Park Building 2 Unit 101
1853 sqft Office • Retail Space • Ft Mill SC

852 Gold Hill Road Fort Mill, SC 29708

Pictures of Special Purpose, Mixed Use, Retail, Office property located at 2025 Bees Ferry Road, Charleston, SC 29414 for sales - image #1
$9,900,000
2025 Bees Ferry Road
Special Purpose • 49,055 SqFt

2025 Bees Ferry Road Charleston, SC 29414

Pictures of Office property located at 321 North Pine Street, Spartanburg, SC 29302 for sales - image #1
$329,000
321 North Pine Street
Office • 1,200 SqFt

321 North Pine Street Spartanburg, SC 29302

Pictures of Office property located at 7358 Garners Ferry Rd, Columbia, SC 29209 for sales - image #1
$2,250,000
7358 Garners Ferry Rd Building
Office • 15,593 SF

7358 Garners Ferry Rd Columbia, SC 29209

Pictures of Retail, Office, Mixed Use property located at 203 S Weston St, Fountain Inn, SC 29644 for sales - image #1
$1,500,000
201-203 South Weston Street
PRIMETIME FOUNTAIN INN COMMERICAL PROPERTY LOCATION

203 S Weston St Fountain Inn, SC 29644

Pictures of Retail, Office, Land property located at 2425 Country Club Road, Spartanburg, SC 29302 for sales - image #1
$1,599,900
2415 & 2425 Country Club Road, Spartanburg, SC
The Intersection of Growth, Visibility, and Opportunity

2425 Country Club Road Spartanburg, SC 29302

Pictures of Industrial, Retail, Office property located at 230 Royle Road, Ladson, SC 29456 for sales - image #1
$9,500,000
230 Royle Road
Industrial • 16,800 SqFt

230 Royle Road Ladson, SC 29456

Pictures of Office, Industrial property located at 4140 Locust Hill Rd, Taylors, SC 29687 for sales - image #1
$950,000
4140 Locust HIll Road
Office • 10,070 SqFt

4140 Locust Hill Rd Taylors, SC 29687

Pictures of Multifamily, Land, Mixed Use, Office property located at 12 John Street, Charleston, SC 29403 for sales - image #1
Opportunity Zone
$2,720,000
12 John Street
Multifamily • 3 Units

12 John Street Charleston, SC 29403

Pictures of Industrial, Office, Special Purpose property located at 1280 Black Hwy, York, SC 29745 for sales - image #1
$800,000
Used Car Dealership 1280 Black Highway
High-visibility Corner Lot Autodealer • 2,400 SqFt

1280 Black Hwy York, SC 29745

Pictures of Retail, Office, Mixed Use property located at 38 New Orleans Rd # B, Hilton Head Island, SC 29928 for sales - image #1
Unpriced
38 New Orleans Road #B
Retail • 4,895 SqFt

38 New Orleans Rd # B Hilton Head Island, SC 29928

South Carolina Office Properties for Sale Market Overview

Search offices for sale in South Carolina and explore 765 office properties for sale on Crexi’s marketplace. Currently, there are 7,484,611 square feet of office space in South Carolina , averaging $1,670,857 and representing $1,171,270,827 in total value. The average price per square foot for offices in South Carolina is $249 with a median cap rate of 6%.



Crexi features South Carolina office units for sale, coworking space for sale, medical office for sale, and more that suit a variety of commercial real estate needs.

Office Properties in South Carolina

Show Less

South Carolina Property Types

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591