www.crexi.com - The Commercial Real Estate Exchange
For Sale
Mixed Use 

South Carolina Mixed Use Properties for Sale

473 results
Pictures of Mixed Use, Office, Retail property located at 1520 American Dr, Florence, SC 29505 for sales - image #1
$3,100,000
1520 American Drive - Proactive MD SC, P.A.
Mixed Use • 6.99% CAP • 9,480 SqFt

1520 American Dr Florence, SC 29505

Pictures of Industrial, Land, Mixed Use, Retail property located at 2000 E River St, Anderson, SC 29621 for sales - image #1
$4,950,000
REDEVELOPMENT OPPORTUNITY WITH 62 ACRES ON US HWY
REDEVELOPMENT OPPORTUNITY OF 62ac

2000 E River St Anderson, SC 29621

Pictures of Mixed Use, Multifamily, Senior Living, Special Purpose property located at 322 W South St, Union, SC 29379 for sales - image #1
$1,975,000
Hospital Adaptive Reuse - Workforce & USC Student Housing
Bailey Bill & Historic Tax Credits - Cost Under $2M - Valued Over $7M

322 W South St Union, SC 29379

Pictures of Mixed Use, Office, Retail, Special Purpose property located at 110 E Greenville St, Anderson, SC 29621 for sales - image #1
Opportunity Zone
$2,300,000
Multi-building/Multi-tenant on Iconic City Block
Mixed Use

110 E Greenville St Anderson, SC 29621

Pictures of Office, Mixed Use, Land property located at 1244 E Butler Rd, Greenville, SC 29607 for sales - image #1
virtual tour
$4,800,000
5.5 ACRES WOODRUFF RD/BUTLER RD BUSY INTERSECTION LOCATION
5.5 ACRES WOODRUFF RD/BUTLER RD BUSY INTERSECTION W/Brick House

1244 E Butler Rd Greenville, SC 29607

Pictures of Retail, Mixed Use, Special Purpose property located at 130 North Elizabeth Lane, Rock Hill, SC 29730 for sales - image #1
virtual tour
Opportunity Zone
$1,200,000
130 & 126 N Elizabeth Ln, Rock Hill SC 29730
Prime Downtown Rock Hill Flex Opportunity • Income + Owner-User Potential • 6,888 sq/ft

130 North Elizabeth Lane Rock Hill, SC 29730

Pictures of Mixed Use, Office, Retail property located at 3598 SC-11, Travelers Rest, SC 29690 for sales - image #1
$2,750,000
Turnkey Class A Luxury Flex Asset with Mark-to-Market Upside
Flex Building • 9.17%+ CAP • 15% Pro Forma CAP

3598 SC-11 Travelers Rest, SC 29690

Pictures of Mixed Use, Land, Self Storage property located at 1111 BERRY SHOALS RD, GREER, SC 29651 for sales - image #1
$2,000,000
1111 BERRY SHOALS RD GREER SC 29651
2 acres - Hwy 101 @ Berry Shoals Rd. Greer, SC

1111 BERRY SHOALS RD GREER, SC 29651

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Hospitality, Land, Mixed Use, Multifamily, Retail property located at Ryobi Drive, Anderson, SC 29621 for sales - image #1
Unpriced
TTI Corporate Crossroads Development Land
TTI Corporate Crossroads Development Land • 21 ac

Ryobi Drive Anderson, SC 29621

Pictures of Retail, Mixed Use property located at 668 N Green St, Ridgeland, SC 29936 for sales - image #1
$1,300,000
668 Green Street
Retail

668 N Green St Ridgeland, SC 29936

Pictures of Industrial, Mixed Use, Land property located at 991 South Guignard Drive, Sumter, SC 29150 for sales - image #1
Unpriced
Lot 4 - S. Guignard Business Park

991 South Guignard Drive Sumter, SC 29150

Pictures of Industrial, Mixed Use property located at 501 Willis Rd, Spartanburg, SC 29301 for sales - image #1
$3,995,000
501 Willis Road
Industrial • 61,289 SqFt

501 Willis Rd Spartanburg, SC 29301

Pictures of Mixed Use, Retail property located at Hwy 707 & Oak Hampton DR, Murrells Inlet, SC 29576 for sales - image #1
$3,271,000
Heartland Dental | Murrells Inlet, SC
5.65% CAP • NEW CONSTRUCTION CORPORATE GUARANTEE

Hwy 707 & Oak Hampton DR Murrells Inlet, SC 29576

Pictures of Hospitality, Mixed Use, Industrial, Retail property located at 3346 U.S. Hwy 301 N, Dillon, SC 29536 for sales - image #1
$2,850,000
3346 Highway 301 N
South of the Border - Dillon, SC - Development Opportunity

3346 U.S. Hwy 301 N Dillon, SC 29536

Pictures of Hospitality, Land, Mixed Use property located at 5506 Platt Springs Rd, Lexington, SC 29073 for sales - image #1
$3,500,000
Red Bank Commercial Development
Mixed Use Development Opportunity • Great for Multifamily & Industrial Developers!

5506 Platt Springs Rd Lexington, SC 29073

Pictures of Hospitality, Land, Mixed Use, Retail, Special Purpose property located at Old Charleston-Augusta Rd, Bamberg, SC 29042 for sales - image #1
$1,150,000
Land for Development // Event Venue for Sale
Hospitality • Retail • Special Purpose

Old Charleston-Augusta Rd Bamberg, SC 29042

Pictures of Hospitality, Mixed Use property located at 695 Elizabeth Dr, Murrells Inlet, SC 29576 for sales - image #1
$1,075,000
Seabatical
Vacation rental- 5 bedrooms, 5.5 baths -.4/mile from The beaches of Garden City, SC

695 Elizabeth Dr Murrells Inlet, SC 29576

Pictures of Mixed Use, Land property located at 510 Smokey Cypress Loop, Aiken, SC 29805 for sales - image #1
$2,200,000
510 Smokey Cypress Loop
Stabilized RV Park 35 Sites w/ 40 More Entitled • 23 Ac • Aiken, SC

510 Smokey Cypress Loop Aiken, SC 29805

Pictures of Industrial, Mixed Use, Office property located at 1212 F R Huff Dr, Saint Matthews, SC 29135 for sales - image #1
$1,200,000
31,200 SF Office/Warehouse/9.8 acres
Prime 31,200 SF Office/Warehouse on 9.8 Acres

1212 F R Huff Dr Saint Matthews, SC 29135

Pictures of Multifamily, Mixed Use, Land property located at 402 Nanaloo Ave, Waterloo, SC 29384 for sales - image #1
$2,100,384
402 Nanaloo Ave.
Multi Generational Lake Front Estate

402 Nanaloo Ave Waterloo, SC 29384

Pictures of Mixed Use, Office property located at 1089 Augusta Rd, Warrenville, SC 29851 for sales - image #1
$1,550,000
18,000 SF office building FOR SALE or LEASE
1089 Augusta Rd Warrenville SC - 18,000 +/- SF

1089 Augusta Rd Warrenville, SC 29851

Pictures of Mixed Use, Retail, Land, Office, Hospitality property located at 48 Bettis Academy Road, Graniteville, SC 29829 for sales - image #1
$2,250,000
48 Bettis Academy Road
Located on the Corner of Interstate 20 and Exit 11.

48 Bettis Academy Road Graniteville, SC 29829

Pictures of Retail, Mixed Use property located at 1704 Bush River Road, Columbia, SC 29210 for sales - image #1
$1,100,000
Hyderabadi house
100% leased Great NOI

1704 Bush River Road Columbia, SC 29210

Pictures of Mixed Use, Office property located at 3095 Soperton Dr, Bluffton, SC 29910 for sales - image #1
$2,950,000
3095 Soperton DR Unit 201
Class A Office/Warehouse Complex Available in Bluffton SC • 5,562 SqFt

3095 Soperton Dr Bluffton, SC 29910

Pictures of Retail, Mixed Use, Land property located at 6218 Savannah Highway, Ravenel, SC 29470 for sales - image #1
$1,300,000
6218 Savannah Highway
Development opportunity in Ravenel SC 15 miles south of Charletson SC

6218 Savannah Highway Ravenel, SC 29470

Pictures of Hospitality, Mixed Use, Multifamily property located at 2010 S Ocean Blvd, Myrtle Beach, SC 29577 for sales - image #1
$6,750,000
2010 S Ocean Blvd
Hospitality

2010 S Ocean Blvd Myrtle Beach, SC 29577

Pictures of Retail, Office, Mixed Use, Land property located at 60 Romney St, Charleston, SC 29403 for sales - image #1
Opportunity Zone
$3,400,000
Redevelopment Opportunity for Sale
Retail • 8,911 SF

60 Romney St Charleston, SC 29403

Pictures of Mixed Use, Multifamily, Office, Retail property located at 104 W Main St, Clinton, SC 29325 for sales - image #1
Opportunity Zone
$289,900
2nd Gen Restaurant - Downtown Clinton
2nd Gen Restaurant - Downtown Clinton

104 W Main St Clinton, SC 29325

Pictures of Mixed Use property located at 2538 Clements Ferry Road, Charleston, SC 29492 for sales - image #1
$4,500,000
2538 Clements Ferry Road
Mixed Use

2538 Clements Ferry Road Charleston, SC 29492

Pictures of Retail, Industrial, Mixed Use, Special Purpose property located at 1253 S Pleasantburg Dr, Greenville, SC 29605 for sales - image #1
$1,100,000
Renovated single NNN tenant flex space - with corner lot
22k VPD with additional corner lot

1253 S Pleasantburg Dr Greenville, SC 29605

Pictures of Retail, Office, Mixed Use property located at West Ashley Circle, Charleston, SC 29414 for sales - image #1
Unpriced
West Ashley Circle
Retail

West Ashley Circle Charleston, SC 29414

Pictures of Industrial, Mixed Use, Special Purpose property located at 533 CREST DR, EASLEY, SC 29640 for sales - image #1
$599,000
533 CREST DR EASLEY SC 29640
Secure 5.7± Acre Industrial Outdoor Storage (IOS) Facility with 4,000 SF Shop

533 CREST DR EASLEY, SC 29640

Pictures of Mixed Use, Hospitality, Multifamily, Office, Retail property located at 691 Bettis Academy Road, Graniteville, SC 29829 for sales - image #1
$1,250,000
691 Bettis Academy Road
Over 500 feet of Road Frontage one lot over from Burger King

691 Bettis Academy Road Graniteville, SC 29829

Pictures of Mixed Use, Land property located at 4800 Sunset Blvd, Lexington, SC 29072 for sales - image #1
$8,000,000
Corley Lumber Yard - 85 AC
84 AC on Sunset Blvd. (Hwy 378)

4800 Sunset Blvd Lexington, SC 29072

Pictures of Hospitality, Mixed Use, Land property located at 195 Ladys Island Dr, Beaufort, SC 29907 for sales - image #1
$1,650,000
195 Ladys Island Dr
Hospitality

195 Ladys Island Dr Beaufort, SC 29907

Pictures of Mixed Use property located at , , , , , , , , , , , , , , , ,  for sales - image #1
Opportunity Zone
Unpriced
Premiere Coast to Coast Mixed Use Investment Opportunities
NATIONWIDE multi-sector Commercial Portfolio offerings - FLEX Mixed Use • 0.00% CAP

17 LOCATIONS

Pictures of Retail, Office, Mixed Use property located at 550 S Church St, Spartanburg, SC 29306 for sales - image #1
$5,500,000
550 S Church St
±45,953 sf strip center for sale or lease

550 S Church St Spartanburg, SC 29306

Pictures of Retail, Office, Mixed Use property located at 302 Park Avenue SE, Aiken, SC 29801 for sales - image #1
video
$2,500,000
144 & 150 Fairfield St SE & 300 - 306 Park Ave SE • Aiken SC
Historic Charm & Modern Convenience • Investment/Owner-User • Office/Retail/Live-Work • Class A

302 Park Avenue SE Aiken, SC 29801

Pictures of Mixed Use, Retail, Special Purpose property located at 101 N 12th St, West Columbia, SC 29169 for sales - image #1
Opportunity Zone
$4,100,000
101 N 12th Street
±54,328 SF Redevelopment Investment Opportunity • Mixed Use

101 N 12th St West Columbia, SC 29169

Pictures of Mixed Use, Office, Retail property located at 1141 Cottingham Blvd N, Bennettsville, SC 29512 for sales - image #1
Unpriced
Former Huddle House
Mixed Use • 2,517 SF

1141 Cottingham Blvd N Bennettsville, SC 29512

Pictures of Retail, Mixed Use property located at 1471 Platt Springs Rd, West Columbia, SC 29169 for sales - image #1
Unpriced
1471 Platt Springs
Retail • 2,284 SqFt

1471 Platt Springs Rd West Columbia, SC 29169

Pictures of Office, Mixed Use property located at 634 Fairview Road, Simpsonville, SC 29680 for sales - image #1
$1,100,000
634 Fairview Road
Prime Office Space in Simpsonville

634 Fairview Road Simpsonville, SC 29680

Pictures of Industrial, Mixed Use, Special Purpose property located at 903 Whitehall Rd, Anderson, SC 29625 for sales - image #1
$325,000
2500sqft Flex Space on 1.89ac
Warehouse • 2,500 SqFt

903 Whitehall Rd Anderson, SC 29625

Pictures of Retail, Mixed Use, Land property located at I-95 Hwy 378, Sumter, SC 29051 for sales - image #1
$1,022,727
I-95 Hwy 378
45 Acres of Commercial Land on I-95

I-95 Hwy 378 Sumter, SC 29051

Pictures of Industrial, Mixed Use, Retail property located at 3841 Richland Ave W, Aiken, SC 29801 for sales - image #1
$895,000
3841 Richland Ave. W
Re-Development Opportunity on Richland Ave. W. - Close Proximity to Aiken Regional Hospital

3841 Richland Ave W Aiken, SC 29801

Pictures of Mixed Use, Retail property located at SC-327, Florence, SC 29506 for sales - image #1
$500,000
1.3 Acres with Hwy 327 access
High traffic counts and great accessibility on Hwy 327

SC-327 Florence, SC 29506

Pictures of Business for Sale, Mixed Use, Office, Retail property located at 1385 Meadow Farm Rd, Inman, SC 29349 for sales - image #1
$1,350,000
Meadow Farm Road
Commercial Property

1385 Meadow Farm Rd Inman, SC 29349

Pictures of Industrial, Mixed Use, Office, Special Purpose property located at 122 E Laurel St, Mullins, SC 29574 for sales - image #1
$1,800,000
122 E Laurel St
Industrial

122 E Laurel St Mullins, SC 29574

Pictures of Mixed Use, Office, Retail property located at 2109 Southport Rd, Spartanburg, SC 29306 for sales - image #1
$1,095,000
Strip mall unit
Mixed Use

2109 Southport Rd Spartanburg, SC 29306

Pictures of Industrial, Mixed Use property located at 2765 Magnolia St, Orangeburg, SC 29115 for sales - image #1
$595,000
Fully Leased Flex Building – Investment Opportunity
Versatile Industrial Property with Tenant in Place – Income-Producing Opportunity

2765 Magnolia St Orangeburg, SC 29115

Pictures of Mixed Use, Retail, Special Purpose property located at 1223 Brickle St, Orangeburg, SC 29118 for sales - image #1
$1,995,000
1223 Brickle Street
±29,000-SF Retail and Mixed-Use Adaptive Reuse Opportunity • Orangeburg, SC

1223 Brickle St Orangeburg, SC 29118

Pictures of Hospitality, Industrial, Mixed Use, Office property located at Florence Harllee Boulevard, Florence, SC 29506 for sales - image #1
Unpriced
±3.25 Acres | Hwy 327 | Additional Acreage Available
Flexible Use • Suitable for QSR, Hospitality, Office or Industrial User

Florence Harllee Boulevard Florence, SC 29506

Pictures of Industrial, Land, Mixed Use, Office, Retail property located at 1551 S Lake Dr, Lexington, SC 29073 for sales - image #1
video
$450,000
1551 S Lake Drive
Redevelopment Opportunity

1551 S Lake Dr Lexington, SC 29073

Pictures of Mixed Use, Mobile Home Park, Multifamily, Office, Senior Living property located at 9133 Two Notch Rd, Columbia, SC 29223 for sales - image #1
$1,200,000
9133 Two Notch Road
1900 sq ft house, but being sold as commercial property.

9133 Two Notch Rd Columbia, SC 29223

Pictures of Mixed Use, Multifamily, Office property located at 112 Rutledge Avenue, Charleston, SC 29401 for sales - image #1
$2,895,000
112 Rutledge Avenue
Mixed Use • 6,873 SqFt

112 Rutledge Avenue Charleston, SC 29401

Pictures of Industrial, Mixed Use, Land property located at 900 South Guignard Drive, Sumter, SC 29150 for sales - image #1
Unpriced
Lot 8 - South Guignard Business Park

900 South Guignard Drive Sumter, SC 29150

Pictures of Mixed Use, Land property located at 30 N HWY 25 BYP, GREENVILLE, SC 29617-1104 for sales - image #1
$2,880,000
±30,000 Sq Ft Heated Warehouse on 5.56 Acres-Travelers Rest
±30,000 SF Heated Warehouse • 5.11 Acres • Travelers Rest

30 N HWY 25 BYP GREENVILLE, SC 29617-1104

Pictures of Industrial, Mixed Use, Retail property located at 10070 Broad River Rd, Irmo, SC 29063 for sales - image #1
$1,950,000
Available for Sale or Lease | Lease Rate: $18.00/SF NNN
Modern Automotive/Flex Facility • Available for Sale or Lease

10070 Broad River Rd Irmo, SC 29063

Pictures of Retail, Office, Mixed Use property located at 52 Wentworth Street # 3, Charleston, SC 29401 for sales - image #1
$1,200,000
52 Wentworth Street #3
Retail • 898 SqFt

52 Wentworth Street # 3 Charleston, SC 29401

Pictures of Mixed Use, Retail property located at 203 Farrs Bridge Rd, Pickens, SC 29671 for sales - image #1
$350,000
Former Auntie Ann's Restaurant (All FF&E Included)
Fully Equipped Restaurant in Pickens, SC

203 Farrs Bridge Rd Pickens, SC 29671

South Carolina Mixed Use Properties for Sale Market Overview

Search mixed use property for sale in South Carolina and explore 477 mixed use real estate for sale on Crexi’s marketplace. Currently, there are 4,717,995 square feet of mixed use property in South Carolina , averaging $1,722,472 and representing $783,724,840 in total value. The average price per square foot for mixed use buildings in South Carolina is $425 with a median cap rate of 5%.


Crexi features South Carolina mixed use developments, mixed use zoning assets, and more that suit a variety of commercial real estate needs.

Mixed Use Properties in South Carolina

Show Less

South Carolina Property Types

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591