www.crexi.com - The Commercial Real Estate Exchange
For Sale
All Types 

Florence, SC Properties for Sale

161 results
Pictures of Land, Mixed Use, Mobile Home Park, Multifamily property located at N Irby St, Florence, SC 29501 for sales - image #1
$193,720
11 Land/Home Sites Florence County, SC MHP or AG Worker MF
Whole Scope Florence County, SC MHP Land/Home Sites or Agriculture Worker Multifamily

N Irby St Florence, SC 29501

Pictures of Land property located at Mechanicsville Rd, Florence, SC 29501 for sales - image #1
$475,000
Mechanicsville Road
±56.55-acre Industrial Development Tract for Sale • Florence, SC

Mechanicsville Rd Florence, SC 29501

Pictures of Land property located at US Hwy 76 and Old Marion Hwy, FLORENCE, SC 29506 for sales - image #1
video
$1,500,000
US Hwy 76 and Old Marion Hwy
Prime Commercial Development Site – US Hwy 76 & Old Marion Hwy • Florence, SC

US Hwy 76 and Old Marion Hwy FLORENCE, SC 29506

Pictures of Land property located at 1000 S Cashua Dr, Florence, SC 29501 for sales - image #1
$995,000
1000 South Cashua Drive
South Cashua • Development Site • 4.768 acres

1000 S Cashua Dr Florence, SC 29501

Pictures of Land property located at S Church St, Florence, SC 29506 for sales - image #1
Unpriced
Church St Development Land
Commercial Land • 7.33 acres • Florence, SC

S Church St Florence, SC 29506

Pictures of Mixed Use, Retail property located at SC-327, Florence, SC 29506 for sales - image #1
$500,000
US Hwy 327 access
1.30 Acres on SC 327 with High Traffic Counts

SC-327 Florence, SC 29506

Pictures of Land property located at 3102 Hoffmeyer Rd, Florence, SC 29501 for sales - image #1
$1,600,000
Hoffmeyer Road
Prime 4.12-Acre Commercial Land For Sale • Hoffmeyer Road & Ebenezer Road • West Florence, SC 29501

3102 Hoffmeyer Rd Florence, SC 29501

Pictures of Retail, Office, Special Purpose property located at 811 South Cashua Drive, Florence, SC 29501 for sales - image #1
$499,000
811 South Cashua Drive
100% Occupied Multi-Tenant Investment Opportunity

811 South Cashua Drive Florence, SC 29501

See New Listings First!
Save your filters and get alerts when new properties hit the market.
Save My Search
Pictures of Retail property located at 2803 West Palmetto Street, Florence, SC 29501 for sales - image #1
$799,000
2803 W Palmetto St
100% Occupied Investment Opportunity

2803 West Palmetto Street Florence, SC 29501

Pictures of Land property located at 700 N CASHUA DR, FLORENCE, SC 29501 for sales - image #1
$499,000
N Cashua Dr & W Sumter St Lot
±1.45 Acre Corner Lot • N Cashua Dr Signalized Intersection

700 N CASHUA DR FLORENCE, SC 29501

Pictures of Land property located at US 76 AND 195, Florence, SC 29501 for sales - image #1
$6,380,000
22 Acre US 76 AND I-95
Land • 22 acres

US 76 AND 195 Florence, SC 29501

Pictures of Land, Retail property located at 2680 PAMPLICO HWY, Florence, SC 29505 for sales - image #1
$495,000
Re-development Site PAMPLICO HWY
Land • 1.75 acres

2680 PAMPLICO HWY Florence, SC 29505

Pictures of Land property located at 2224 Hoffmeyer Rd, Florence, SC 29501 for sales - image #1
$799,000
2224 & 2216 Hoffmeyer Rd
Redevelopment Site • Florence, SC

2224 Hoffmeyer Rd Florence, SC 29501

Pictures of Land property located at 1622 W Palmetto St, Florence, SC 29501 for sales - image #1
$1,300,000
1622 West Palmetto Street | ±2.897 Acres
2.897 Acres • Development Site • For Sale

1622 W Palmetto St Florence, SC 29501

Pictures of Land property located at W Palmetto St, Florence, SC 29501 for sales - image #1
$250,000/Acre
Subdivisible Land for Commercial Purpose(7.99Acres)
Land • 7.99 acres

W Palmetto St Florence, SC 29501

Pictures of Land property located at S Irby Street, Florence, SC 29505 for sales - image #1
$258,000
South Irby Street & Millstone Drive
Land • 0.74 acres

S Irby Street Florence, SC 29505

Pictures of Land property located at Freedom Blvd, Florence, SC 29505 for sales - image #1
Unpriced
±130 Acres | For Sale | Freedom Blvd | Florence, SC
±130 Acres • For Sale • Freedom Blvd • Florence, SC

Freedom Blvd Florence, SC 29505

Pictures of Land property located at David H McLeod Blvd, Florence, SC 29501 for sales - image #1
Unpriced
Development Sites | I-95 & I-20 Intersection
Land • ±108 acres • Subdivisible

David H McLeod Blvd Florence, SC 29501

Pictures of Industrial, Mixed Use, Office, Retail property located at 1826 Sally Hill Farms Blvd, Florence, SC 29501 for sales - image #1
video
$925,000
1826 Sally Hill Farms Blvd.
Florence, SC 8,000 SF Industrial Flex Building

1826 Sally Hill Farms Blvd Florence, SC 29501

Pictures of Land property located at Mountain Laurel Ct, Florence, SC 29505 for sales - image #1
$300,000
±1.741 Acres | Development Site | For Sale
±1.741 ACRES • DEVELOPMENT SITE • FOR SALE

Mountain Laurel Ct Florence, SC 29505

Pictures of Land property located at Hwy 176 Highway E, Holly Hill, SC 29503 for sales - image #1
$225,000
Atkinson Property
Land • 3.4 acres

Hwy 176 Highway E Holly Hill, SC 29503

Pictures of Land property located at 420 2nd Loop Rd, Florence, SC 29505 for sales - image #1
$1,850,000
420 Second Loop Road
±7.21 Acres • Second Loop Road • Land

420 2nd Loop Rd Florence, SC 29505

Pictures of Land property located at 3rd Loop Rd, Florence, SC 29505 for sales - image #1
$110,000
±0.389 Acres | Third Loop Road | Development Site
Land • 0.389 acres

3rd Loop Rd Florence, SC 29505

Pictures of Retail property located at 3311 E Palmetto St, Florence, SC 29506 for sales - image #1
$775,000
Dollar General Florence
Fantastic 1031 Exchange Property DG is Publicly Traded BBB Rated Investment Grade

3311 E Palmetto St Florence, SC 29506

Pictures of Land property located at Dozier Blvd, Florence, SC 29501 for sales - image #1
$1,300,000
Dozier Blvd - 3.679 Acres
Land • 3.679 acres

Dozier Blvd Florence, SC 29501

Pictures of Land property located at US HWY 76 & 301, Florence, SC 29506 for sales - image #1
$800,000
Parcel by Frances Marion - Florence, SC 29506
Land • 4.61 acres

US HWY 76 & 301 Florence, SC 29506

Pictures of Land property located at 118 N. Cashua Drive, Florence, SC 29501 for sales - image #1
$795,000
118 N. Cashua Drive, Florence SC - 3.5 Acre Development Site
Cashua Drive Development Site • 3.5 acres

118 N. Cashua Drive Florence, SC 29501

Pictures of Land property located at Hoffmeyer rd and Dozier Blvd, Florence, SC 29501 for sales - image #1
$350,000
Hoffmeyer Rd & Dozier Blvd
Land • 5.6 acres

Hoffmeyer rd and Dozier Blvd Florence, SC 29501

Pictures of Hospitality property located at 2038 W Lucas St, Florence, SC 29501 for sales - image #1
Unpriced
Howard Johnson by Wyndham Florence
106 Keys • Includes Standalone Home • I-95 Location

2038 W Lucas St Florence, SC 29501

Pictures of Land property located at 3540 Hoffmeyer Rd, Florence, SC 29501 for sales - image #1
$4,530,000
TBD Hoffmeyer Road
Development Opportunity • +/- 168 acres • West Florence

3540 Hoffmeyer Rd Florence, SC 29501

Pictures of Land property located at 1050 Freedom Blvd, Florence, SC 29506 for sales - image #1
$870,000
1050 Freedom Blvd
Land • 4.65 acres

1050 Freedom Blvd Florence, SC 29506

Pictures of Land property located at 210 N Cashua Dr, Florence, SC 29501 for sales - image #1
$1,200,000
Tyler Land Company - 210 N. Cashua Drive - 5.47 acres
Cashua Drive Development Site • 5.47 acres

210 N Cashua Dr Florence, SC 29501

Pictures of Land property located at 1649 East Palmetto Street, Florence, SC 29506 for sales - image #1
Opportunity Zone
$145,000
1649 E PALMETTO ST
1649 E. Palmetto Street – Florence, SC Prime Commercial Corner Site • 1.32 Acres • CMU Zoning

1649 East Palmetto Street Florence, SC 29506

Pictures of Retail, Special Purpose property located at 702 S Barringer St, Florence, SC 29501 for sales - image #1
Opportunity Zone
$200,000
702 S Barringer Street
Retail • 1,520 SF

702 S Barringer St Florence, SC 29501

Pictures of Land property located at TBD Jody Rd, Florence, SC 29501 for sales - image #1
$330,000
TBD Jody Road
W Jody Rd • Land • 1.10 acres

TBD Jody Rd Florence, SC 29501

Pictures of Land property located at 2423 David H McLeod Blvd, Florence, SC 29501 for sales - image #1
Unpriced
Redevelopment 2423 W David McLeod Blvd
Land • 2.32 acres

2423 David H McLeod Blvd Florence, SC 29501

Pictures of Land property located at 703 S Church St, Florence, SC 29501 for sales - image #1
Opportunity Zone
$50,000
703 S Church Street
Land • 0.16 acres

703 S Church St Florence, SC 29501

Pictures of Land property located at TV Rd, Florence, SC 29506 for sales - image #1
$625,000
TV Road | Florence, SC
Land • 20 acres

TV Rd Florence, SC 29506

Pictures of Land property located at N Ebenezer Rd, Florence, SC 29501 for sales - image #1
$430,000
±12.28 Acres | N Ebenezer Rd, Florence, SC
12.28 acres • N Ebenezer Rd, Florence, SC

N Ebenezer Rd Florence, SC 29501

Pictures of Land property located at 704 S Barringer St, Florence, SC 29501 for sales - image #1
Opportunity Zone
$95,000
704 S Barringer Street
Land • 0.16 acres

704 S Barringer St Florence, SC 29501

Pictures of Retail, Mixed Use, Land property located at East Howe Springs Road, Florence, SC 29505 for sales - image #1
$1,300,000
East Howe Springs Road
15± acres • City limits • Water & Sewer in place • 113-unit townhouse layout approved — also viable

East Howe Springs Road Florence, SC 29505

Pictures of Land property located at 1956 W Darlington St, Florence, SC 29501 for sales - image #1
$495,000
Tyler Darlington Street Site - 3.17 acres
Land • 3.17 acres

1956 W Darlington St Florence, SC 29501

Pictures of Land property located at 01 Dozier Blvd, Florence, SC 29501 for sales - image #1
$675,000
Dozier Blvd - 2.69 Acres
Land • 2.69 acres

01 Dozier Blvd Florence, SC 29501

Pictures of Retail property located at 158 South Cashua Drive, Florence, SC 29501 for sales - image #1
$499,000
South Cashua Dr & King Ave
100% Occupied Investment Opportunity • 5 Buildings • 6 Tenants

158 South Cashua Drive Florence, SC 29501

Pictures of Land property located at 0000 W Lucas St, Florence, SC 29501 for sales - image #1
$820,670
0000 W Lucas St
Land • 8.4 acres

0000 W Lucas St Florence, SC 29501

Pictures of Office property located at 181 E Evans St, Florence, SC 29506 for sales - image #1
Opportunity Zone
$12,000,000
181 E Evans Street - Florence Business Technology Center
Value-Add Opportunity in the Heart of Downtown Florence • ±119,567 SF Office Building for Sale

181 E Evans St Florence, SC 29506

Pictures of Land property located at 2730 W PALMETTO ST, FLORENCE, SC 29501-5930 for sales - image #1
$750,000
W Palmetto St & Jefferson Dr Lot
±2.23 Acres • High Traffic Location

2730 W PALMETTO ST FLORENCE, SC 29501-5930

Pictures of Land property located at 3025 W Palmetto Street, Florence, SC 29501 for sales - image #1
$285,000
3025 W Palmetto Street
Land • 1 acres

3025 W Palmetto Street Florence, SC 29501

Pictures of Land property located at 2nd Loop Rd, Florence, SC 29505 for sales - image #1
$575,000
Second Loop Rd & Damon Dr
Hard Corner • Second Loop Rd & Damon Dr • ±1.14 Acres

2nd Loop Rd Florence, SC 29505

Pictures of Land property located at 611 S Irby St, Florence, SC 29501 for sales - image #1
Opportunity Zone
$395,000
±1.05 Acres | 611 S Irby St | Florence, SC
Additional Acreage Available

611 S Irby St Florence, SC 29501

Pictures of Land property located at 601 S Church St, Florence, SC 29506 for sales - image #1
Opportunity Zone
$125,000
601 S Church Street
Land • 0.33 acres

601 S Church St Florence, SC 29506

Pictures of Hospitality, Multifamily property located at ,  for sales - image #1
$7,800,000
USVI _ DEVELOPER OFFERING_ AS-IS 10 KEYS
Rare Condo Development Opportunity, Luxury Residences

2 LOCATIONS

Pictures of Retail, Special Purpose property located at 710 S Barringer St, Florence, SC 29501 for sales - image #1
Opportunity Zone
$400,000
Formerly Southeast Vending
Retail • 3,375 SqFt

710 S Barringer St Florence, SC 29501

Pictures of Land property located at S Cashua Dr, Florence, SC 29501 for sales - image #1
$465,000
Cashua Drive 2.33 acres
Land • 2.33 acres

S Cashua Dr Florence, SC 29501

Pictures of Land property located at TBD KIGHT RD, Florence, SC 29501 for sales - image #1
$35,000
TBD KIGHT RD
Land • 3.38 SqFt

TBD KIGHT RD Florence, SC 29501

Pictures of Retail property located at 233 W Lucas St, Florence, SC 29501 for sales - image #1
$998,000
233 W Lucas St.
Retail • 8.50% CAP • 9,180 SqFt

233 W Lucas St Florence, SC 29501

Pictures of Land property located at 517 S Church St, Florence, SC 29506 for sales - image #1
Opportunity Zone
$160,000
517 S Church Street
Land • 0.87 acres

517 S Church St Florence, SC 29506

Pictures of Land property located at 3083 TV Rd, Florence, SC 29501 for sales - image #1
Unpriced
3083 TV Road
1 to 22.65 acres • Commercial Land • I-95 and TV Road

3083 TV Rd Florence, SC 29501

Pictures of Land property located at Quartz Lane, Florence, SC 29506 for sales - image #1
$630,000
TBD Quartz Lane
Land • 3.5 acres

Quartz Lane Florence, SC 29506

Pictures of Land property located at TBD W Leggs Cir, Florence, SC 29501 for sales - image #1
$129,900
TBD W Leggs Cir
Land • 4 acres

TBD W Leggs Cir Florence, SC 29501

Results per page:

Florence, SC Properties for Sale Market Overview

Check out commercial properties for sale in Florence, SC only on Crexi. Crexi features Florence self storage for sale, land for sale, retail space for sale, offices, industrial properties, and more that suit a variety of commercial real estate needs.

Currently, there are 156 commercial real estate listings available in Florence, representing $146,436,754 with an average price of $1,162,196. The average price per square foot in Florence is $147 with a median cap rate of 7%

In Florence, the average price for:

Industrial properties is $2,933,000

Retail properties is $1,040,510

Office properties is $2,192,545

Multifamily properties is $1,260,294

Nearby Properties

Show Less

Florence Property Types

Show Less
For assistance, reach out to our support team at [email protected] or call 888.273.0423 . For press inquiries, contact [email protected]
Equal Housing Opportunity
5510 Lincoln Blvd #400, Los Angeles, CA 90094Commercial Real Estate Exchange, Inc.Crexi Technologies, LLCCXTechnology, LLC
© 2026 Commercial Real Estate Exchange, Inc. All Rights Reserved. DRE #02086591